SCHEMBL15745679

SCHEMBL15745679

Cc1cc(Cc2cc(C)c(N3C(=O)c4ccc(S(=O)(=O)c5ccc6c(c5)C(=O)N(C)C6=O)cc4C3=O)c(C(C)(O)C(F)(F)F)c2)cc(C(C)(O)C(F)(F)F)c1C

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
ANPEP P15144 1/20 0.32
DPP4 P27487 1/20 0.32
HSD11B1 P28845 4/20 0.31
POLB P06746 1/20 0.31
CNR2 P34972 1/20 0.31
KDM4E B2RXH2 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15745681 0.89 ANPEP (0.34) ALDH1A1ANPEPDPP4KDM4E
SCHEMBL15745680 0.86 ANPEP (0.33) ANPEPDPP4
SCHEMBL15745683 0.86 ALDH1A1 (0.35) ALDH1A1ANPEPDPP4KDM4E
SCHEMBL15745682 0.86 ALDH1A1 (0.34) ALDH1A1ANPEPDPP4POLBKDM4E
SCHEMBL15722888 0.82 ALDH1A1 (0.49) ALDH1A1ANPEPDPP4POLBKDM4E
SCHEMBL15745817 0.79 ALDH1A1 (0.35) ALDH1A1HSD11B1
SCHEMBL15745686 0.75 ALDH1A1 (0.44) ALDH1A1ANPEPDPP4HSD11B1POLB
SCHEMBL14678933 0.72 CA1 (0.38) ALDH1A1ANPEPDPP4POLB
SCHEMBL15831660 0.71 AR (0.39)
SCHEMBL15826862 0.69 ANPEP (0.42) ALDH1A1ANPEPDPP4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9793483-B2 Hexafluoroisopropanol group-containing diamine, polyimide and polyamide using same, cyclized product thereof, and method for producing same CENTRAL GLASS COMPANY, LIMITED (JP) 2017-10-17 US disclosed
US-20140148571-A1 Hexafluoroisopropanol Group-Containing Diamine, Polyimide And Polyamide Using Same, Cyclized Product Thereof, And Method For Producing Same CENTRAL GLASS COMPANY, LIMITED (JP) 2014-05-29 US disclosed