SCHEMBL15745682

SCHEMBL15745682

Cc1cc(Cc2cc(C)c(N3C(=O)c4ccc(Oc5ccc6c(c5)C(=O)N(C)C6=O)cc4C3=O)c(C(C)(O)C(F)(F)F)c2)cc(C(C)(O)C(F)(F)F)c1C

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.34
MEN1 O00255 5/20 0.34
KMT2A Q03164 5/20 0.34
KDM4E B2RXH2 2/20 0.34
HTT P42858 2/20 0.34
LPAR1 Q92633 1/20 0.34
LPAR3 Q9UBY5 1/20 0.34
MAPK1 P28482 1/20 0.34
HSD17B10 Q99714 1/20 0.34
PKM P14618 1/20 0.33
BRD4 O60885 1/20 0.33
ANPEP P15144 1/20 0.33
DPP4 P27487 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
POLB P06746 1/20 0.32
DRD1 P21728 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
F2 P00734 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15745681 0.90 ANPEP (0.34) ALDH1A1MEN1KMT2AKDM4EMAPK1
SCHEMBL15745683 0.87 ALDH1A1 (0.35) ALDH1A1KMT2AKDM4EANPEPDPP4
SCHEMBL15745680 0.87 ANPEP (0.33) ANPEPDPP4
SCHEMBL15745679 0.86 ALDH1A1 (0.41) ALDH1A1KDM4EANPEPDPP4POLB
SCHEMBL15745823 0.79 NR1H2 (0.31) ALDH1A1MEN1KMT2ABRD4ANPEP
SCHEMBL15745685 0.74 ALDH1A1 (0.37) ALDH1A1MEN1KMT2AKDM4EHTT
SCHEMBL13223040 0.72 ANPEP (0.41) ALDH1A1MEN1KMT2AKDM4EHTT
SCHEMBL15831660 0.71 AR (0.39)
SCHEMBL15826862 0.70 ANPEP (0.42) ALDH1A1MEN1KMT2AKDM4EMAPK1
SCHEMBL15745684 0.70 PGR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9793483-B2 Hexafluoroisopropanol group-containing diamine, polyimide and polyamide using same, cyclized product thereof, and method for producing same CENTRAL GLASS COMPANY, LIMITED (JP) 2017-10-17 US disclosed
US-20140148571-A1 Hexafluoroisopropanol Group-Containing Diamine, Polyimide And Polyamide Using Same, Cyclized Product Thereof, And Method For Producing Same CENTRAL GLASS COMPANY, LIMITED (JP) 2014-05-29 US disclosed