SCHEMBL15745995

SCHEMBL15745995

CC(C)(C)c1ccc(-n2c3ccccc3c3cc(N(c4ccccc4)c4ccccc4)ccc32)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.45
ATM Q13315 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
PPARG P37231 9/20 0.42
PPARA Q07869 3/20 0.40
CYP2D6 P10635 1/20 0.36
ALDH1A1 P00352 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
NR1H4 Q96RI1 1/20 0.35
PMM2 O15305 1/20 0.35
MPI P34949 1/20 0.35
PHOSPHO1 Q8TCT1 1/20 0.35
PGR P06401 1/20 0.34
RORA P35398 1/20 0.34
RORC P51449 1/20 0.34
RORB Q92753 1/20 0.34
MAPK8 P45983 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15746010 0.97 KDM4E (0.49) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL12117332 0.95 KDM4E (0.46) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL15746015 0.94 KDM4E (0.50) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL24030005 0.94 KDM4E (0.41) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL10087119 0.93 KDM4E (0.47) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL15746000 0.93 KDM4E (0.44) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL16230989 0.93 KDM4E (0.46) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL10098623 0.93 KDM4E (0.39) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL24030007 0.92 KDM4E (0.42) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL23514021 0.92 KDM4E (0.41) KDM4EATML3MBTL1PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190319194-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-10-17 US disclosed
US-10381569-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 US disclosed
US-9997712-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-9997712-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-9512136-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-12-06 US disclosed
US-20160149139-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-05-26 US disclosed
US-8927749-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-01-06 US disclosed
US-20140291638-A1 HOST MATERIALS FOR OLED APPLICATION UNIVERSAL DISPLAY CORPORATION (US) 2014-10-02 US disclosed
US-20140252318-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2014-09-11 US disclosed
US-20140145149-A1 Organic Luminescent Compound With Delayed Fluorescence UNIVERSAL DISPLAY CORPORATION (US) 2014-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140145149-A1 Organic Luminescent Compound With Delayed Fluorescence OCIAD1, OCIAD2, MLYCD KDM4E 3261/4885ATM 2395/4885L3MBTL1 303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.