SCHEMBL15746010

SCHEMBL15746010

CC(C)(C)c1ccc(N(c2ccccc2)c2ccc3c(c2)c2ccccc2n3-c2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.49
ATM Q13315 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
PPARG P37231 4/20 0.40
PPARA Q07869 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
MAPK8 P45983 1/20 0.36
CYP2D6 P10635 1/20 0.36
HPGD P15428 2/20 0.36
CYP1A2 P05177 1/20 0.36
GLA P06280 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
HSD17B10 Q99714 1/20 0.35
PGR P06401 2/20 0.34
RORA P35398 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15745995 0.97 KDM4E (0.45) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL10087119 0.96 KDM4E (0.47) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL12117332 0.95 KDM4E (0.46) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL25749630 0.93 KDM4E (0.47) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL25011819 0.93 KDM4E (0.47) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL1982509 0.93 KDM4E (0.42) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL1981817 0.93 KDM4E (0.42) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL23057807 0.92 KDM4E (0.49) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL10087147 0.92 KDM4E (0.40) KDM4EATML3MBTL1PPARGPPARA
SCHEMBL15746002 0.92 KDM4E (0.40) KDM4EATML3MBTL1PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12029111-B2 Oxygen heterocyclic compound, application thereof and electronic device using the same WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-07-02 US disclosed
US-12029111-B2 Oxygen heterocyclic compound, application thereof and electronic device using the same WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-07-02 US disclosed
US-20230041564-A1 OXYGEN HETEROCYCLIC COMPOUND, APPLICATION THEREOF AND ELECTRONIC DEVICE USING THE SAME WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-02-09 US disclosed
US-20190319194-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-10-17 US disclosed
US-10381569-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 US disclosed
US-9512136-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-12-06 US disclosed
US-20160149139-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-05-26 US disclosed
US-20140145149-A1 Organic Luminescent Compound With Delayed Fluorescence UNIVERSAL DISPLAY CORPORATION (US) 2014-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12029111-B2 Oxygen heterocyclic compound, application thereof and electronic device using the same AOC2, AOX1, TYR KDM4E 706/4885ATM 1755/4885L3MBTL1 3116/4885
US-20140145149-A1 Organic Luminescent Compound With Delayed Fluorescence OCIAD1, OCIAD2, MLYCD KDM4E 3261/4885ATM 2395/4885L3MBTL1 303/4885
US-20230041564-A1 OXYGEN HETEROCYCLIC COMPOUND, APPLICATION THEREOF AND ELECTRONIC DEVICE USING THE SAME AOC2, AOX1, TYR KDM4E 706/4885ATM 1755/4885L3MBTL1 3116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.