Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.57 |
| ▸ | LPL | P06858 | 11/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 11/20 | 0.44 |
| ▸ | F11 | P03951 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15747843 | 0.96 | DGAT1 (0.57) | DGAT1LPLLIPGF11GRM5 | |
| SCHEMBL21125909 | 0.90 | DGAT1 (0.67) | DGAT1LPLLIPG | |
| SCHEMBL30739 | 0.86 | DGAT1 (0.70) | DGAT1LPLLIPGCYP11B1CYP11B2 | |
| SCHEMBL29688361 | 0.86 | DGAT1 (0.70) | DGAT1LPLLIPGCYP11B1CYP11B2 | |
| SCHEMBL19933582 | 0.86 | DGAT1 (0.62) | DGAT1LPLLIPG | |
| SCHEMBL13584509 | 0.85 | DGAT1 (0.55) | DGAT1LPLLIPGGRM5CYP11B1 | |
| SCHEMBL20068614 | 0.85 | DGAT1 (0.56) | DGAT1LPLLIPGF11 | |
| SCHEMBL16787665 | 0.84 | DGAT1 (0.61) | DGAT1LPLLIPGCYP3A4CYP2A6 | |
| SCHEMBL19933583 | 0.84 | DGAT1 (0.55) | DGAT1LPLLIPG | |
| SCHEMBL18015506 | 0.83 | DGAT1 (0.60) | DGAT1LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078241-A1 | AROMATIC AMINE DERIVATIVES AND PREPARATION METHOD AND MEDICAL USE THEREOF | 中国医药研究开发中心有限公司 | 2023-05-11 | — | — | WO | disclosed |
| WO-2014079364-A1 | IMIDAZOLONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | 北京富龙康泰生物技术有限公司 (CN) | 2014-05-30 | — | — | WO | disclosed |