SCHEMBL30739

SCHEMBL30739

CC1(C)OB(c2ccc(-c3ccccc3)nc2)OC1(C)C

nearest known ligand 0.70

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 2/20 0.70
LIPG Q9Y5X9 9/20 0.62
LPL P06858 8/20 0.62
PDGFRB P09619 1/20 0.42
KDR P35968 1/20 0.42
LDHA P00338 1/20 0.40
P4HB P07237 1/20 0.40
CYP11B1 P15538 2/20 0.39
CYP11B2 P19099 2/20 0.39
BAZ2B Q9UIF8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29688361 1.00 DGAT1 (0.70) DGAT1LIPGLPLPDGFRBKDR
SCHEMBL18015662 0.97 DGAT1 (0.70) DGAT1LIPGLPLPDGFRBKDR
SCHEMBL15747808 0.95 DGAT1 (0.69) DGAT1LIPGLPLPDGFRBKDR
SCHEMBL21125909 0.92 DGAT1 (0.67) DGAT1LIPGLPLPDGFRBKDR
SCHEMBL18015663 0.90 DGAT1 (0.59) DGAT1LIPGLPLPDGFRBKDR
SCHEMBL29293266 0.89 LIPG (0.71) DGAT1LIPGLPLPDGFRBKDR
SCHEMBL21125910 0.89 DGAT1 (0.57) DGAT1LIPGLPLPDGFRBKDR
SCHEMBL793065 0.87 DGAT1 (0.63) DGAT1LIPGLPLPDGFRBKDR
SCHEMBL19933582 0.87 DGAT1 (0.62) DGAT1LIPGLPLPDGFRBKDR
SCHEMBL20176546 0.87 DGAT1 (0.56) DGAT1LIPGLPLPDGFRBKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092053-A1 KHK INHIBITORS GILEAD SCIENCES INC (US) 2026-04-02 US disclosed
US-20260055127-A1 METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENCE DEVICES UDC IRELAND LTD (IE) 2026-02-26 US disclosed
EP-4681774-A2 KHK INHIBITORS Gilead Sciences, Inc. (US) 2026-01-21 EP disclosed
US-12479873-B2 Metal complexes UDC Ireland (IE) 2025-11-25 US disclosed
EP-4313967-B1 KHK INHIBITORS GILEAD SCIENCES INC (US) 2025-11-12 EP disclosed
US-12454542-B2 Metal complexes for use as emitters in organic electroluminescence devices UDC IRELAND LIMITED (IE) 2025-10-28 US disclosed
US-12410160-B2 KHK inhibitors GILEAD SCIENCES, INC. (US) 2025-09-09 US disclosed
US-20250268910-A1 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS PHILIP MORRIS PRODUCTS S.A. (CH) 2025-08-28 US disclosed
US-12127470-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-10-22 US disclosed
US-20240300989-A1 METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENCE DEVICES UDC IRELAND LTD (IE) 2024-09-12 US disclosed
US-20110065738-A1 POLYCYCLIC GUANINE DERIVATIVES AND USE THEREOF SCHERING CORPORATION 2011-03-17 US disclosed
WO-2011002887-A1 FUSED TRICYCLIC COMPOUNDS AS NOVEL mTOR INHIBITORS SCHERING CORPORATION (US) 2011-01-06 WO disclosed
WO-2011002887-A1 FUSED TRICYCLIC COMPOUNDS AS NOVEL mTOR INHIBITORS SCHERING CORPORATION (US) 2011-01-06 WO disclosed
WO-2010118207-A1 PYRAZOLO [1, 5-A] PYRIMIDINE DERIVATIVES AS MTOR INHIBITORS SCHERING CORPORATION (US) 2010-10-14 WO disclosed
WO-2010118207-A1 PYRAZOLO [1, 5-A] PYRIMIDINE DERIVATIVES AS MTOR INHIBITORS SCHERING CORPORATION (US) 2010-10-14 WO disclosed
WO-2010027583-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-03-11 WO disclosed
WO-2010027583-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-03-11 WO disclosed
WO-2010028151-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-03-11 WO disclosed
WO-2010028151-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2010-03-11 WO disclosed
WO-2009002423-A2 POLYCYCLIC GUANINE DERIVATIVES AND USE THEREOF SCHERING CORPORATION (US) 2008-12-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12454542-B2 Metal complexes for use as emitters in organic electroluminescence devices ICMT, ORAI2, AOC2 DGAT1 2614/4885LIPG 4819/4885LPL 4753/4885
US-12479873-B2 Metal complexes AP1M1, SOD1, AP3M1 DGAT1 2093/4885LIPG 3352/4885LPL 3378/4885
US-20240300989-A1 METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENCE DEVICES ICMT, ORAI2, AOC2 DGAT1 2614/4885LIPG 4819/4885LPL 4753/4885
US-12127470-B2 Organic electroluminescent materials and devices SOD1, CLTB, L1CAM DGAT1 4690/4885LIPG 3545/4885LPL 3973/4885
US-20260092053-A1 KHK INHIBITORS KHK, SLC5A2, HK1 DGAT1 1085/4885LIPG 249/4885LPL 178/4885
US-12410160-B2 KHK inhibitors KHK, KHDRBS1, NADK DGAT1 3451/4885LIPG 2261/4885LPL 3327/4885
US-20110065738-A1 POLYCYCLIC GUANINE DERIVATIVES AND USE THEREOF GDA, HPRT1, GMPS DGAT1 1438/4885LIPG 4777/4885LPL 4817/4885
US-20260055127-A1 METAL COMPLEXES FOR USE AS EMITTERS IN ORGANIC ELECTROLUMINESCENCE DEVICES SCO2, ROS1, MT-CO1 DGAT1 2560/4885LIPG 4604/4885LPL 4678/4885
US-20250268910-A1 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS CHRNA1, CHRNG, CHRM3 DGAT1 3640/4885LIPG 2872/4885LPL 1909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.