Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 5/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.43 |
| ▸ | MTOR | P42345 | 9/20 | 0.43 |
| ▸ | ATR | Q13535 | 3/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 3/20 | 0.41 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.41 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | LTK | P29376 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15747848 | 0.91 | USP30 (0.41) | ATMPIK3CAMTORATRPIK3CD | |
| SCHEMBL15747794 | 0.90 | DDB1 (0.41) | ATMPIK3CAMTORPIK3CDDDB1 | |
| SCHEMBL15747763 | 0.85 | PIK3CA (0.42) | ATMPIK3CAMTORATRPIK3CD | |
| SCHEMBL15747740 | 0.85 | DDB1 (0.43) | DDB1CRBNSYKJAK3RET | |
| SCHEMBL15747888 | 0.84 | MTOR (0.43) | ATMPIK3CAMTORATRPIK3CD | |
| SCHEMBL16748243 | 0.84 | MTOR (0.61) | ATMPIK3CAMTORATRPRKDC | |
| SCHEMBL15747850 | 0.83 | MTOR (0.59) | ATMPIK3CAMTORATRPIK3CD | |
| SCHEMBL31439339 | 0.83 | MTOR (0.42) | ATMPIK3CAMTORATRPIK3CD | |
| SCHEMBL31439325 | 0.81 | MTOR (0.56) | PIK3CAMTORPIK3CDPIK3CGPIK3CB | |
| SCHEMBL16748212 | 0.81 | MTOR (0.55) | ATMPIK3CAMTORATRUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014079364-A1 | IMIDAZOLONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | 北京富龙康泰生物技术有限公司 (CN) | 2014-05-30 | — | — | WO | disclosed |