Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15747814 | 0.90 | ATM (0.43) | DDB1CRBNMEN1KMT2ANPSR1 | |
| SCHEMBL15747740 | 0.83 | DDB1 (0.43) | DDB1CRBNMEN1KMT2ANPSR1 | |
| SCHEMBL15747871 | 0.83 | MTOR (0.52) | PIK3CAMTORATMPIK3CDRET | |
| SCHEMBL21913308 | 0.82 | MTOR (0.44) | PIK3CAMTORATMPIK3CD | |
| SCHEMBL15747848 | 0.82 | USP30 (0.41) | PIK3CAMTORATMPIK3CD | |
| SCHEMBL15747758 | 0.81 | MTOR (0.40) | DDB1CRBNSYKPIK3CAMTOR | |
| SCHEMBL15747763 | 0.78 | PIK3CA (0.42) | MEN1KMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL16748243 | 0.76 | MTOR (0.61) | PIK3CAMTORATM | |
| SCHEMBL15747821 | 0.75 | HPGDS (0.42) | LMNAALDH1A1PIK3CAHPGDHSD17B10 | |
| SCHEMBL15747888 | 0.75 | MTOR (0.43) | LMNAPIK3CAMTORNAMPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014079364-A1 | IMIDAZOLONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | 北京富龙康泰生物技术有限公司 (CN) | 2014-05-30 | — | — | WO | disclosed |