Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 9/20 | 0.42 |
| ▸ | MTOR | P42345 | 9/20 | 0.42 |
| ▸ | ATM | Q13315 | 4/20 | 0.41 |
| ▸ | ATR | Q13535 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.40 |
| ▸ | JAK3 | P52333 | 3/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | JAK1 | P23458 | 2/20 | 0.40 |
| ▸ | TYK2 | P29597 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PIK3C2A | O00443 | 2/20 | 0.39 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15747831 | 0.89 | ADORA2A (0.47) | PIK3CAMTORATMATRPIK3CD | |
| SCHEMBL15747730 | 0.88 | MTOR (0.55) | PIK3CAMTORATMATRPIK3CD | |
| SCHEMBL15747772 | 0.87 | MTOR (0.55) | PIK3CAMTORATMATRPIK3CD | |
| SCHEMBL15747812 | 0.86 | MTOR (0.57) | PIK3CAMTORATMATRPIK3CD | |
| SCHEMBL15747888 | 0.86 | MTOR (0.43) | PIK3CAMTORATMATRPIK3CD | |
| SCHEMBL15747811 | 0.86 | ATM (0.52) | PIK3CAMTORATMATRPIK3CD | |
| SCHEMBL15747851 | 0.85 | MTOR (0.45) | PIK3CAMTORATMATRPIK3CD | |
| SCHEMBL15747876 | 0.85 | MTOR (0.45) | PIK3CAMTORATMATRPIK3CD | |
| SCHEMBL15747814 | 0.85 | ATM (0.43) | PIK3CAMTORATMATRPIK3CD | |
| SCHEMBL15747771 | 0.85 | GRIN2B (0.42) | PIK3CAMTORPDE4BJAK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014079364-A1 | IMIDAZOLONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | 北京富龙康泰生物技术有限公司 (CN) | 2014-05-30 | — | — | WO | disclosed |