Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17192553 | 0.86 | CHRM1 (0.33) | RAB9AMEN1KMT2ACHRM1 | |
| SCHEMBL15748132 | 0.85 | RAB9A (0.35) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL18025086 | 0.83 | CHRM2 (0.34) | RAB9AMEN1KMT2ACHRM1NPC1 | |
| SCHEMBL23636368 | 0.82 | RAB9A (0.33) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL18891429 | 0.82 | RAB9A (0.34) | RAB9AMEN1KMT2ACHRM1NPC1 | |
| SCHEMBL15748083 | 0.82 | RAB9A (0.32) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL15747928 | 0.77 | ALDH1A1 (0.35) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL15748113 | 0.77 | MAPT (0.35) | RAB9AMEN1KMT2ACHRM1MAPT | |
| SCHEMBL3671896 | 0.77 | RAB9A (0.33) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL3671892 | 0.77 | RAB9A (0.33) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4245744-A2 | CHEMICALLY CLEAVABLE GROUP | Tagworks Pharmaceuticals B.V. (NL) | 2023-09-20 | — | — | EP | disclosed |
| WO-2014081299-A1 | ACTIVATABLE LIPOSOMES | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2014-05-30 | — | — | WO | disclosed |