SCHEMBL1574832

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1575229	0.84	GRIN2B (0.45)	MAPTS1PR2GRIN2BPAK1
	SCHEMBL1574810	0.82	CCR2 (0.47)	MAPTS1PR2GRIN2BSHMT2PAK1
	SCHEMBL1576237	0.81	GAA (0.47)	S1PR2GRIN2BSHMT2PAK1
	SCHEMBL1575624	0.81	GAA (0.47)	S1PR2GRIN2BSHMT2PAK1
	SCHEMBL1575401	0.79	GRIN2B (0.45)	MAPTS1PR2GRIN2BPAK1
	SCHEMBL1575699	0.79	GRIN2B (0.45)	MAPTS1PR2GRIN2BPAK1
	SCHEMBL1575049	0.79	DCUN1D1 (0.46)	S1PR2GRIN2BPAK1
	SCHEMBL1575349	0.78	CYP2C9 (0.47)	MEN1KMT2AS1PR2NAMPTGRIN2B
	SCHEMBL1575524	0.78	CCR2 (0.45)	MAPTS1PR2TACR1GRIN2BPAK1
	SCHEMBL1574330	0.78	MAPT (0.53)	MAPTNAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.