Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 4/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | PARL | Q9H300 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15748456 | 0.89 | BCHE (0.56) | LMNAGAAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL15748451 | 0.83 | SNCA (0.44) | LMNAGAAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL15748450 | 0.83 | NOX1 (0.46) | LMNAGAAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL15748457 | 0.82 | CA1 (0.43) | BCHEACHE | |
| SCHEMBL15748452 | 0.82 | BCHE (0.54) | LMNAGAAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL5915315 | 0.82 | MEN1 (0.48) | MAPTSMN1; SMN2BCHEACHECTSG | |
| SCHEMBL29381701 | 0.71 | HDAC3 (0.56) | LMNAMAPTMAPK1SMN1; SMN2BCHE | |
| SCHEMBL27083986 | 0.71 | HDAC3 (0.56) | LMNAMAPTMAPK1SMN1; SMN2BCHE | |
| SCHEMBL22481364 | 0.70 | P2RX4 (0.62) | LMNAGAAMAPTBCHECTSG | |
| SCHEMBL8870652 | 0.70 | MAPT (0.47) | LMNAGAAMAPTMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014080378-A1 | PHENOTHIAZINE DERIVATIVES AND THEIR USE AGAINST TUBERCULOSIS | UNIVERSITY OF CAPE TOWN (ZA) | 2014-05-30 | — | — | WO | disclosed |