Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.62 |
| ▸ | BCHE | P06276 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5915315 | 0.83 | MEN1 (0.48) | P2RX4BCHEMAPTCTSGCMA1 | |
| SCHEMBL15748456 | 0.80 | BCHE (0.56) | BCHECA1CA2MAPTLMNA | |
| SCHEMBL29394903 | 0.77 | P2RX4 (1.00) | P2RX4L3MBTL1CA1CA2LMNA | |
| SCHEMBL8739567 | 0.74 | MAOA (0.54) | BCHEMAPTGAAMAOA | |
| SCHEMBL29172142 | 0.72 | L3MBTL1 (0.65) | P2RX4BCHEL3MBTL1CA1CA2 | |
| SCHEMBL29436330 | 0.72 | L3MBTL1 (0.65) | P2RX4L3MBTL1CA1CA2HTT | |
| SCHEMBL1412652 | 0.72 | L3MBTL1 (0.65) | P2RX4L3MBTL1CA1CA2HTT | |
| SCHEMBL189167 | 0.71 | ALDH1A1 (0.55) | P2RX4L3MBTL1CA1CA2HTT | |
| SCHEMBL31371562 | 0.71 | MAPT (0.59) | P2RX4MAPTLMNAGAANPSR1 | |
| SCHEMBL31371249 | 0.70 | KCNN4 (0.47) | P2RX4BCHECA1CA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200306258-A1 | TARGETING THE TLK1/NEK1 AXIS IN PROSTATE CANCER | UNITED STATES GOVERNMENT | 2020-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200306258-A1 | TARGETING THE TLK1/NEK1 AXIS IN PROSTATE CANCER | NEK11, NEK1, NEK10 | P2RX4 4738/4885BCHE 4051/4885L3MBTL1 618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.