SCHEMBL15748728

SCHEMBL15748728

CC1(C)OB(c2ccc3[nH]c4cc5c(ccn5-c5ccccc5)cc4c3c2)OC1(C)C

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LPL P06858 2/20 0.37
LIPG Q9Y5X9 2/20 0.37
PRMT5 O14744 1/20 0.34
WDR77 Q9BQA1 1/20 0.34
IRAK4 Q9NWZ3 1/20 0.33
IDO1 P14902 1/20 0.32
TDO2 P48775 1/20 0.32
PLA2G4A P47712 1/20 0.31
P4HB P07237 1/20 0.30
ROCK1 Q13464 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15748672 0.85 LPL (0.37) LPLLIPGPRMT5WDR77IRAK4
SCHEMBL15748727 0.82 LPL (0.39) LPLLIPGPRMT5WDR77IRAK4
SCHEMBL15596458 0.81 LPL (0.38) LPLLIPGPRMT5WDR77IRAK4
SCHEMBL15596499 0.81 LPL (0.38) LPLLIPGPRMT5WDR77IRAK4
SCHEMBL15533400 0.81 LPL (0.46) LPLLIPGIRAK4PLA2G4AP4HB
SCHEMBL28356410 0.80 LIPG (0.55) LPLLIPGPRMT5WDR77IRAK4
SCHEMBL15596388 0.77 AHR (0.50) PLA2G4A
SCHEMBL20715158 0.77 LPL (0.46) LPLLIPGPRMT5WDR77
SCHEMBL29396069 0.77 LPL (0.46) LPLLIPGPRMT5WDR77
SCHEMBL1542754 0.76 LPL (0.47) LPLLIPGPRMT5WDR77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014081133-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 (KR) 2014-05-30 WO disclosed
WO-2014081147-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 (KR) 2014-05-30 WO disclosed