SCHEMBL15751663

SCHEMBL15751663

[CH2]CC(C)OC(=O)C(=C)C

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.48
ALDH1A1 P00352 2/20 0.42
THRB P10828 1/20 0.36
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM1 P11229 1/20 0.34
TBXA2R P21731 1/20 0.34
GALR3 O60755 1/20 0.33
MAPT P10636 1/20 0.33
BLM P54132 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2540758 0.84 TSHR (0.50) TSHRALDH1A1THRBCHRM2CHRM4
SCHEMBL2544205 0.84 TSHR (0.50) TSHRALDH1A1THRBCHRM2CHRM4
SCHEMBL27635138 0.83 TSHR (0.45) TSHRALDH1A1THRBCHRM2CHRM4
SCHEMBL27785078 0.82 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL2013862 0.82 TSHR (0.54) TSHRALDH1A1THRBCHRM2CHRM4
SCHEMBL15318827 0.82 TSHR (0.48) TSHRALDH1A1THRBCHRM2CHRM4
SCHEMBL204713 0.82 TSHR (0.48) TSHRALDH1A1THRBCHRM2CHRM4
SCHEMBL377956 0.82 TSHR (0.48) TSHRALDH1A1THRBCHRM2CHRM4
SCHEMBL33467 0.82 TSHR (0.48) TSHRALDH1A1THRBCHRM2CHRM4
SCHEMBL2349785 0.80 TSHR (0.47) TSHRALDH1A1THRBCHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102762655-A Surface-modified hydrogels and hydrogel microparticles DOW CORNING 2012-10-31 CN claimed
CN-102666665-A Silicone compositions comprising a swollen silicone gel DOW CORNING 2012-09-12 CN claimed
CN-107743492-B Process for preparing acryloxysilanes 美国陶氏有机硅公司 2020-07-17 CN disclosed
CN-106413755-B Medical instrument containing negative ionic drugs 株式会社SEED 2019-09-03 CN disclosed
CN-106604937-A Curable composition 住友化学株式会社 2017-04-26 CN disclosed
CN-106413755-A Medical device including anionic drug 株式会社SEED 2017-02-15 CN disclosed
EP-2738610-B1 Electrophotographic photosensitive member, method for producing electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KK (JP) 2016-02-03 EP disclosed
US-9034545-B2 Electrophotographic photosensitive member, method for producing electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-05-19 US disclosed
US-20140154617-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2014-06-05 US disclosed
EP-2738610-A1 Electrophotographic photosensitive member, method for producing electrophotographic photosensitive member, process cartridge and electrophotographic apparatus Canon Kabushiki Kaisha (JP) 2014-06-04 EP disclosed
CN-102762655-A Surface-modified hydrogels and hydrogel microparticles DOW CORNING 2012-10-31 CN disclosed
CN-102666665-A Silicone compositions comprising a swollen silicone gel DOW CORNING 2012-09-12 CN disclosed
CN-101085916-B Organic electroluminescence or charge transmission material containing olefine acid ester side group and synthesis thereof DONGGUAN ANWELL DIGITAL MACH 2012-06-06 CN disclosed
CN-101085916-A Organic electroluminescence or charge transmission material containing olefine acid ester side group and synthesis thereof SHANGHAI TOYOU DIGITAL TECHNOL (CN) 2007-12-12 CN disclosed
CN-100334122-C (meth)acrylamide polymer, process for production thereof, paper making chemicals, papers containing the same NIPPON PMC K K (JP) 2007-08-29 CN disclosed
CN-1636026-A (meth) acrylamide polymer, method for producing same, chemical for papermaking, and paper containing same NIPPON PMC K K (JP) 2005-07-06 CN disclosed