Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.50 |
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | LMNA | P02545 | 7/20 | 0.50 |
| ▸ | HTT | P42858 | 6/20 | 0.50 |
| ▸ | TP53 | P04637 | 6/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PTPRB | P23467 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1576966 | 0.86 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL31117253 | 0.85 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL963107 | 0.85 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL1286389 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL31117574 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL962048 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL20183231 | 0.74 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL1576637 | 0.74 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL2976178 | 0.73 | ALDH1A1 (0.69) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL12398243 | 0.73 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNAHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308510-B1 | Agent for regeneration and/or protection of nerves | ONO PHARMACEUTICAL CO (JP) | 2016-03-16 | — | — | EP | disclosed |
| US-20130143934-A1 | AGENT FOR REGENERATION AND/OR PROTECTION OF NERVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-06-06 | — | — | US | disclosed |
| US-8404858-B2 | Agent for regeneration and/or protection of nerves | ONO PHARMACEUTICAL CO., LTD. (JP) | 2013-03-26 | — | — | US | disclosed |
| EP-2494990-A1 | Agent for regeneration and/or protection of nerves | ONO PHARMACEUTICAL CO., LTD. (JP) | 2012-09-05 | — | — | EP | disclosed |
| EP-2308510-A1 | Agent for regeneration and/or protection of nerves | Ono Pharmaceutical Co., Ltd. (JP) | 2011-04-13 | — | — | EP | disclosed |
| US-20110059920-A1 | AGENT FOR REGENERATION AND/OR PROTECTION OF NERVES | ONO PHARMACEUTICAL CO., LTD (JP) | 2011-03-10 | — | — | US | disclosed |
| US-7863263-B2 | Agent for regeneration and/or protection of nerves | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-01-04 | — | — | US | disclosed |
| US-20090227644-A1 | AGENT FOR REGENERATION AND/OR PROTECTION OF NERVES | ONO PHARMACEUTICAL CO., LTD (JP) | 2009-09-10 | — | — | US | disclosed |
| EP-1886693-A1 | AGENT FOR REGENERATION AND/OR PROTECTION OF NERVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130143934-A1 | AGENT FOR REGENERATION AND/OR PROTECTION OF NERVES | PTGER3, PTGER2, PTGER1 | ALDH1A1 1947/4885MAPT 4554/4885LMNA 777/4885 |
| US-20090227644-A1 | AGENT FOR REGENERATION AND/OR PROTECTION OF NERVES | PTGER3, PTGER2, PTGER1 | ALDH1A1 1947/4885MAPT 4554/4885LMNA 777/4885 |
| US-20110059920-A1 | AGENT FOR REGENERATION AND/OR PROTECTION OF NERVES | PTGER3, PTGER2, PTGER1 | ALDH1A1 1947/4885MAPT 4554/4885LMNA 777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.