Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.58 |
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | LMNA | P02545 | 7/20 | 0.53 |
| ▸ | HTT | P42858 | 7/20 | 0.53 |
| ▸ | TP53 | P04637 | 5/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12398239 | 0.90 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL12464772 | 0.90 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL21482478 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL21486317 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL25761013 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL2978401 | 0.79 | ALDH1A1 (0.71) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL16075755 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL21464648 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL21482480 | 0.78 | ALDH1A1 (0.61) | ALDH1A1MAPTLMNAHTTTP53 | |
| SCHEMBL21464429 | 0.78 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNAHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212136-B2 | Methods for producing paricalcitol | AZAD PHARMACEUTICALS INGREDIENTS AG (CH) | 2015-12-15 | — | — | US | disclosed |
| US-20110184199-A1 | Methods For Producing Paricalcitol | AZAD PHARMA AG (CH) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184199-A1 | Methods For Producing Paricalcitol | CYP2R1, PTH1R, CYP24A1 | ALDH1A1 3875/4885MAPT 3142/4885LMNA 1839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.