SCHEMBL15760416

SCHEMBL15760416

Cc1cccc(Oc2ccc(C3(c4ccc(Oc5cccc(Oc6ccc(S(=O)(=O)c7ccc(Oc8cccc(C)c8C#N)cc7)cc6)c5C#N)cc4)c4ccccc4-c4ccccc43)cc2)c1C#N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.43
HSD11B1 P28845 1/20 0.41
HTT P42858 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PTGS2 P35354 1/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
AR P10275 3/20 0.33
BCL2L1 Q07817 1/20 0.33
MCL1 Q07820 1/20 0.33
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
OPRK1 P41145 1/20 0.33
KMT2A Q03164 1/20 0.33
GPR119 Q8TDV5 3/20 0.32
TSHR P16473 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15760408 0.90 ESR1 (0.40) MAPTHSD11B1HTTSMN1; SMN2L3MBTL1
SCHEMBL14264195 0.88 MAPT (0.55) MAPTHSD11B1HTTSMN1; SMN2L3MBTL1
SCHEMBL12960254 0.85 POLB (0.47) MAPTHSD11B1HTTSMN1; SMN2L3MBTL1
SCHEMBL15760415 0.84 MAPT (0.53) MAPTHSD11B1HTTSMN1; SMN2TDP1
SCHEMBL15760417 0.81 AR (0.37) MAPTHSD11B1SMN1; SMN2ESR1ESR2
SCHEMBL26572702 0.81 PKM (0.50) MAPTHSD11B1HTTSMN1; SMN2TDP1
SCHEMBL15760413 0.81 ESR1 (0.34) MAPTSMN1; SMN2ESR1ESR2AR
SCHEMBL13910401 0.80 MAPT (0.33) MAPTHSD11B1
SCHEMBL12425090 0.79 PKM (0.51) MAPTHSD11B1HTTSMN1; SMN2TDP1
SCHEMBL18179341 0.79 LMNA (0.36) MAPTHSD11B1SMN1; SMN2KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9764276-B2 Resin composition and carbon dioxide gas separation membrane SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-09-19 US disclosed
US-20160158692-A1 RESIN COMPOSITION AND CARBON DIOXIDE GAS SEPARATION MEMBRANE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-06-09 US disclosed
US-20140154610-A1 AROMATIC COPOLYMER HAVING PROTON CONDUCTIVE GROUP AND USES THEREOF JSR CORPORATION (JP) 2014-06-05 US disclosed