Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | FLT3 | P36888 | 2/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL878011 | 0.84 | KDM5B (0.38) | RXRARXRBRXRGKDM5BALDH1A1 | |
| SCHEMBL35212261 | 0.82 | FLT3 (0.38) | RXRARXRBRXRGKDM5BALDH1A1 | |
| SCHEMBL29525193 | 0.81 | KDM5B (0.40) | RXRARXRBRXRGKDM5BALDH1A1 | |
| SCHEMBL31510377 | 0.81 | KDM5B (0.40) | RXRARXRBRXRGKDM5BALDH1A1 | |
| SCHEMBL22774288 | 0.81 | KDM5B (0.40) | RXRARXRBRXRGKDM5BALDH1A1 | |
| SCHEMBL13035401 | 0.81 | GABRA1 (0.39) | RXRARXRBRXRGKDM5BALDH1A1 | |
| SCHEMBL31562893 | 0.78 | RXRA (0.42) | RXRARXRBRXRGKDM5BALDH1A1 | |
| SCHEMBL31180433 | 0.78 | KDM5B (0.36) | RXRARXRBRXRGKDM5BALDH1A1 | |
| SCHEMBL15286385 | 0.78 | KDM5B (0.39) | RXRARXRBRXRGKDM5BALDH1A1 | |
| SCHEMBL17714250 | 0.76 | CYP4F2 (0.43) | RXRARXRBRXRGKDM5BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014084312-A1 | IMIDAZOPYRIDINE COMPOUND | アステラス製薬株式会社 (JP) | 2014-06-05 | — | — | WO | disclosed |