Uridine

Uridine

SCHEMBL157643

O=P(O)(O)O.O=c1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.90

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Known targets — ChEMBL curated mechanism

ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Uridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.90
SLC28A2 O43868 1/20 0.90
SLC29A1 Q99808 1/20 0.90
SLC28A3 Q9HAS3 1/20 0.90
P2RY2 P41231 11/20 0.74
P2RY6 Q15077 8/20 0.69
P2RY4 P51582 4/20 0.68
P2RY14 Q15391 7/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uridine SCHEMBL30094506 1.00 SLC28A1 (0.90) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL29801499 1.00 SLC28A1 (0.90) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL28065954 1.00 SLC28A1 (0.90) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL376208 1.00 SLC28A1 (0.90) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL76681 1.00 SLC28A1 (0.90) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL28131489 0.99 SLC28A1 (0.88) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL17074124 0.99 SLC28A1 (0.88) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL2370972 0.99 SLC28A1 (0.88) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL17439380 0.95 SLC28A1 (0.85) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL5330850 0.95 SLC28A1 (0.85) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5422 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4401580-B1 SOLID COMPOSITION SUITABLE AS A NUTRITIONAL COMPOSITION OR SUPPLEMENT FOR ANIMALS THAT SUFFER FROM BRAIN RELATED DISORDERS, DECLINE OR DISEASES NUTRICIA NV (NL) 2026-05-27 EP claimed
EP-4748443-A2 SOLID COMPOSITION SUITABLE AS A NUTRITIONAL COMPOSITION OR SUPPLEMENT FOR ANIMALS THAT SUFFER FROM BRAIN RELATED DISORDERS, DECLINE OR DISEASES N.V. Nutricia (NL) 2026-05-27 EP claimed
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2026-04-30 US claimed
US-20260098284-A1 CELL-FREE PPi-DRIVEN ATP REGENERATION PLATFORM TYMOSHENKO STEPAN (US) 2026-04-09 US claimed
US-20260063623-A1 METHODS OF ASSESSING METABOLIC FLUX UNIV MICHIGAN REGENTS (US) 2026-03-05 US claimed
US-20260034171-A1 Composition for Improving Cognitive Function PERRY STEPHEN C (US) 2026-02-05 US claimed
US-12533371-B2 Multilayer pharmaceutical or nutraceutical solid dosage forms comprising pyrimidine and/or purine derivatives and b vitamins, preparation and uses thereof FERRER INTERNACIONAL, S.A. (ES) 2026-01-27 US claimed
US-20250277216-A1 Allele-Specific Silencing of Transforming Growth Factor Beta Induced Gene with R124H Mutation Using Short Interfering RNA AVELLINO LAB USA, INC. (CA) 2025-09-04 US claimed
EP-4602365-A2 METHODS OF ASSESSING METABOLIC FLUX The Regents of The University of Michigan (US) 2025-08-20 EP claimed
WO-2000020045-A1 DEVICE FOR TREATMENT OF BIOLOGICAL FLUIDS COMMON SERVICES AGENCY (GB) 2000-04-13 WO claimed
US-5866378-A Process for the synthesis of nucleotide-6-deoxy-D-xylo-4-hexuloses HOECHST AKTIENGESELLSCHAFT (DE) 1999-02-02 US claimed
WO-1995016785-A1 USE OF THERMOPHILIC BACTERIA TO MANUFACTURE TRIAZOLE NUCLEOSIDES OPACIC GORDANA (YU) 1995-06-22 WO claimed
EP-0538268-A4 TARGETED PROTECTION FROM CYTOTOXINS 1993-05-12 EP claimed
EP-0538268-A1 TARGETED PROTECTION FROM CYTOTOXINS THE UNIVERSITY OF CONNECTICUT (US) 1993-04-28 EP claimed
EP-0484266-A2 Fat mixture for infant and adult nutrition PULEVA UNION INDUSTRIAL Y AGRO-GANADERA, S.A. (ES) 1992-05-06 EP claimed
WO-1991017761-A1 TARGETED PROTECTION FROM CYTOTOXINS THE UNIVERSITY OF CONNECTICUT (US) 1991-11-28 WO claimed
CN-1056530-A Saccharides and synthetic method thereof and equipment UNIV PENNSYLVANIA (US) 1991-11-27 CN claimed
US-5009994-A Uniform distribution EM DIAGNOSTIC SYSTEMS, INC. (US) 1991-04-23 US claimed
EP-0343783-A2 Method for producing cells containing stably integrated foreign DNA at a high copy number, the cells produced by this method, and the use of these cells to produce the polypeptides coded for by the foreign DNA BTG USA INC (US) 1989-11-29 EP claimed