Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12985051 | 0.89 | ALDH1A1 (0.39) | RAB9AALDH1A1NPC1HPGDHSD17B10 | |
| SCHEMBL13192363 | 0.86 | — | — | |
| SCHEMBL15764437 | 0.84 | CA12 (0.34) | ALDH1A1HPGDHSD17B10NPSR1SMN1; SMN2 | |
| Butyramide SCHEMBL12986515 | 0.82 | — | — | |
| Butyramide SCHEMBL15422000 | 0.82 | — | — | |
| SCHEMBL15422640 | 0.78 | NPC1 (0.38) | RAB9ANPC1 | |
| SCHEMBL12986662 | 0.77 | SLC6A2 (0.47) | RAB9AALDH1A1NPC1HPGDHSD17B10 | |
| SCHEMBL15764399 | 0.75 | RAB9A (0.38) | RAB9AALDH1A1NPC1HPGDHSD17B10 | |
| SCHEMBL12985701 | 0.74 | SLC6A2 (0.45) | — | |
| SCHEMBL15764398 | 0.73 | HSD17B10 (0.38) | RAB9AALDH1A1NPC1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748466-B2 | Isoxazole derivatives useful as antibacterial agents | PFIZER INC. (US) | 2014-06-10 | — | — | US | disclosed |