SCHEMBL15765748

SCHEMBL15765748

COC(=O)c1cc2c(cc1CCO)C(=O)OC2=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.41
CYP4A11 Q02928 2/20 0.41
GABRA1 P14867 2/20 0.39
GABRG2 P18507 2/20 0.39
GABRB3 P28472 2/20 0.39
GABRA3 P34903 2/20 0.39
CA12 O43570 2/20 0.38
CA7 P43166 2/20 0.38
CA2 P00918 1/20 0.38
CA3 P07451 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
CA5B Q9Y2D0 1/20 0.38
NPC1 O15118 1/20 0.38
KDM4E B2RXH2 4/20 0.38
ALDH1A1 P00352 3/20 0.38
LMNA P02545 2/20 0.38
GLA P06280 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31192519 0.82 KDM4E (0.46) GABRA1GABRG2GABRB3GABRA3CA12
SCHEMBL23043890 0.75 CYP4A11 (0.47) CYP4F2CYP4A11CA12CA7CA2
SCHEMBL20107566 0.73 THRB (0.40) CA2KDM4EALDH1A1LMNAPOLB
SCHEMBL21423118 0.72 ALDH1A1 (0.41) GABRA1GABRG2GABRB3GABRA3CA12
SCHEMBL24032919 0.71 POLB (0.40) GABRA1GABRG2GABRB3GABRA3CA12
SCHEMBL16978020 0.71 THRB (0.39) GABRA1GABRG2GABRB3GABRA3CA12
SCHEMBL2655484 0.70 ALDH1A1 (0.70) CYP4F2CYP4A11CA2CA5ACA9
SCHEMBL9062686 0.70 NPC1 (0.57) CYP4F2CYP4A11CA12CA7CA2
SCHEMBL12855242 0.69 KDM4E (0.41) GABRA1GABRG2GABRB3GABRA3CA12
SCHEMBL29082757 0.69 CA12 (0.49) CYP4F2CYP4A11CA12CA7CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014084188-A1 FLUORINE-CONTAINING POLYMERIZABLE MONOMER AND POLYMER COMPOUND USING SAME セントラル硝子株式会社 (JP) 2014-06-05 WO disclosed