⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12306859 | 0.87 | LPAR2 (0.33) | — | |
| SCHEMBL5146750 | 0.82 | — | — | |
| SCHEMBL1559671 | 0.82 | LPAR2 (0.35) | — | |
| SCHEMBL12306857 | 0.81 | BTN3A1 (0.38) | — | |
| SCHEMBL10495971 | 0.78 | LPAR2 (0.31) | — | |
| SCHEMBL7633961 | 0.78 | FDPS (0.43) | — | |
| SCHEMBL2459231 | 0.75 | LPAR2 (0.31) | — | |
| SCHEMBL3956656 | 0.70 | — | — | |
| SCHEMBL23037249 | 0.70 | — | — | |
| SCHEMBL30645 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483283-B1 | Method for the manufacture of aminohydroxy diphosphonic acids | STRAITMARK HOLDING AG (CH) | 2015-01-07 | — | — | EP | disclosed |
| US-8779135-B2 | Method for the manufacture of aminohydroxy diphosphonic acids | STRAITMARK HOLDING AG (CH) | 2014-07-15 | — | — | US | disclosed |
| US-20120245354-A1 | METHOD FOR THE MANUFACTURE OF AMINOHYDROXY DIPHOSPHONIC ACIDS | STRAITMARK HOLDING AG (CH) | 2012-09-27 | — | — | US | disclosed |
| EP-2483283-A1 | METHOD FOR THE MANUFACTURE OF AMINOHYDROXY DIPHOSPHONIC ACIDS | Straitmark Holding AG (CH) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011039378-A1 | METHOD FOR THE MANUFACTURE OF AMINOHYDROXY DIPHOSPHONIC ACIDS | STRAITMARK HOLDING AG (CH) | 2011-04-07 | — | — | WO | disclosed |