Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3485080 | 0.84 | TSHR (0.50) | TSHRNPSR1RXFP1SIRT2NPC1 | |
| SCHEMBL11088928 | 0.77 | TSHR (0.50) | TSHRNPSR1RXFP1SIRT2NPC1 | |
| SCHEMBL640172 | 0.75 | TSHR (0.54) | TSHRNPSR1RXFP1SIRT2NPC1 | |
| SCHEMBL8804817 | 0.71 | TSHR (0.50) | TSHRNPSR1RXFP1SIRT2NPC1 | |
| SCHEMBL8889223 | 0.70 | TSHR (0.45) | TSHRNPSR1RXFP1SIRT2NPC1 | |
| SCHEMBL12246376 | 0.69 | TSHR (0.51) | TSHRNPSR1RXFP1SIRT2NPC1 | |
| SCHEMBL8804705 | 0.69 | TSHR (0.47) | TSHRNPSR1RXFP1SIRT2NPC1 | |
| SCHEMBL23146638 | 0.69 | TSHR (0.54) | TSHRNPSR1RXFP1SIRT2NPC1 | |
| SCHEMBL8404027 | 0.68 | TSHR (0.58) | TSHRNPSR1RXFP1SIRT2NPC1 | |
| SCHEMBL8804149 | 0.68 | TSHR (0.50) | TSHRNPSR1RXFP1SIRT2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9296973-B2 | Lubricating oil composition for use in all transmission systems | PETROCHINA COMPANY LIMITED (CN) | 2016-03-29 | — | — | US | claimed |
| US-20140162919-A1 | LUBRICATING OIL COMPOSITION FOR USE IN ALL TRANSMISSION SYSTEMS | PETROCHINA COMPANY LIMITED (CN) | 2014-06-12 | — | — | US | claimed |
| US-9296973-B2 | Lubricating oil composition for use in all transmission systems | PETROCHINA COMPANY LIMITED (CN) | 2016-03-29 | — | — | US | disclosed |
| US-20140162919-A1 | LUBRICATING OIL COMPOSITION FOR USE IN ALL TRANSMISSION SYSTEMS | PETROCHINA COMPANY LIMITED (CN) | 2014-06-12 | — | — | US | disclosed |