Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3485080 | 0.90 | TSHR (0.50) | TSHRNPSR1RXFP1SIRT2POLB | |
| SCHEMBL8804817 | 0.83 | TSHR (0.50) | TSHRNPSR1RXFP1SIRT2POLB | |
| SCHEMBL8889223 | 0.81 | TSHR (0.45) | TSHRNPSR1RXFP1SIRT2POLB | |
| SCHEMBL8804705 | 0.80 | TSHR (0.47) | TSHRNPSR1RXFP1SIRT2POLB | |
| SCHEMBL8804149 | 0.79 | TSHR (0.50) | TSHRNPSR1RXFP1SIRT2HDAC3 | |
| SCHEMBL15768655 | 0.77 | TSHR (0.42) | TSHRNPSR1RXFP1SIRT2POLB | |
| SCHEMBL239516 | 0.77 | SIRT2 (0.60) | TSHRNPSR1RXFP1SIRT2POLB | |
| SCHEMBL30140830 | 0.77 | SIRT2 (0.60) | TSHRNPSR1RXFP1SIRT2POLB | |
| SCHEMBL8806232 | 0.76 | TSHR (0.48) | TSHRNPSR1RXFP1SIRT2HDAC3 | |
| SCHEMBL266156 | 0.76 | TSHR (0.48) | TSHRNPSR1RXFP1SIRT2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0105486-A2 | 1-Monophosphate esters, 1,3-bisphosphate esters and cyclic phosphate esters of 9-(1,3-dihydroxy-2-propoxymethyl)-guanine as antiviral agents | SYNTEX (U.S.A.) INC. (US) | 1984-04-18 | — | — | EP | disclosed |