SCHEMBL1576931

SCHEMBL1576931

NS(=O)(=O)Cc1ccccc1C1=NOCCS1

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 1/20 0.35
FEN1 P39748 1/20 0.35
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA5A P35218 2/20 0.33
CA9 Q16790 2/20 0.33
CA12 O43570 1/20 0.33
LMNA P02545 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
MAOB P27338 1/20 0.33
CA7 P43166 1/20 0.33
CA13 Q8N1Q1 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1576994 0.81
SCHEMBL1576692 0.79 CA1 (0.36) ALOX5APFEN1CA1CA2CA5A
SCHEMBL8633929 0.75 ALOX5AP (0.36) ALOX5APFEN1CA1CA2CA5A
SCHEMBL1577258 0.72 CA1 (0.33) CA1CA2CA9CA12CA4
SCHEMBL1577055 0.66 L3MBTL1 (0.32)
SCHEMBL11065594 0.66 DPP4 (0.55) ALOX5APFEN1CA1CA2CA5A
SCHEMBL8875554 0.65 HPGD (0.33) ALOX5APFEN1CA1CA2CA9
SCHEMBL1576938 0.64 PLK1 (0.31)
SCHEMBL1576746 0.64
SCHEMBL4712987 0.63 HSPA5 (0.52) CA1CA2CA5ACA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011039276-A1 OXATHIAZINYL(HET)ARYLSULFONYLUREAS, PROCESSES AND INTERMEDIATES FOR PREPARATION THEREOF AND USE THEREOF AS CROP PROTECTION AGENTS AND CROP GROWTH REGULATORS BAYER CROPSCIENCE AG (DE) 2011-04-07 WO disclosed