Dichlorofluorescein

Dichlorofluorescein

SCHEMBL157703

O=C1OC2(c3cc(Cl)c(O)cc3Oc3cc(O)c(Cl)cc32)c2ccccc21

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.64
MEN1 O00255 5/20 0.64
KMT2A Q03164 5/20 0.64
TDP1 Q9NUW8 4/20 0.64
FTO Q9C0B1 3/20 0.64
HTT P42858 2/20 0.64
RECQL P46063 2/20 0.64
BLM P54132 2/20 0.64
PRMT1 Q99873 2/20 0.64
ACE2 Q9BYF1 2/20 0.64
CYP2C19 P33261 2/20 0.64
HPGD P15428 1/20 0.64
SMAD3 P84022 1/20 0.64
GNG2 P59768 1/20 0.53
GNB1 P62873 1/20 0.53
LMNA P02545 5/20 0.52
USP2 O75604 2/20 0.52
ALDH1A1 P00352 2/20 0.52
CYP3A4 P08684 3/20 0.50
POLB P06746 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dichlorofluorescein SCHEMBL30606648 1.00 MAPT (0.64) MAPTMEN1KMT2ATDP1FTO
Dichlorofluorescein SCHEMBL29364373 1.00 MAPT (0.64) MAPTMEN1KMT2ATDP1FTO
Dichlorofluorescein SCHEMBL25207800 0.99 MAPT (0.63) MAPTMEN1KMT2ATDP1FTO
Dichlorofluorescein SCHEMBL28221705 0.95 MAPT (0.59) MAPTMEN1KMT2ATDP1FTO
Dichlorofluorescein SCHEMBL21196869 0.94 MAPT (0.57) MAPTMEN1KMT2ATDP1FTO
SCHEMBL4173117 0.93 FTO (0.79) MAPTMEN1KMT2ATDP1FTO
SCHEMBL29871701 0.93 FTO (0.79) MAPTMEN1KMT2ATDP1FTO
SCHEMBL15801068 0.93 MAPT (0.56) MAPTMEN1KMT2ATDP1FTO
SCHEMBL10145452 0.91 MAPT (0.54) MAPTMEN1KMT2ATDP1FTO
SCHEMBL10176074 0.91 MAPT (0.54) MAPTMEN1KMT2ATDP1FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6419 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070479-A Ultrasonic indicating device and method for monitoring ultrasonic treatment JP实验室股份有限公司 2026-05-19 CN claimed
US-20260132218-A1 FULLY HUMAN MONOCLONAL ANTIBODIES AGAINST HUMAN HER-2 A & G PHARMACEUTICAL INC (US) 2026-05-14 US claimed
US-12605484-B2 Two-component system for the therapeutic treatment of skin lesions and production method thereof DTECH - SOCIETÀ A RESPONSABILITÀ LIMITATA (IT) 2026-04-21 US claimed
WO-2026043246-A1 METHOD FOR DETECTING HYDROGEN PEROXIDE BY UTILIZING SELF-BIOTINYLATION OF GUANINE QUADRUPLEX 한국과학기술원 2026-02-26 WO claimed
US-20250327794-A1 FLUOROMETRIC METHODS FOR DETECTION OF ALLERGIC SENSITIVITY TO ENVIRONMENTAL, FOODSTUFF, AND MEDICAMENT STIMULANTS CELL SCIENCE SYSTEMS CORPORATION (US) 2025-10-23 US claimed
US-20250195432-A1 METHODS FOR PREPARING AND CHARACTERIZING ZEIN-FUCOIDAN CONJUGATED NANO-LIPOSOME FOR PHYTOL ENCAPSULATION ZHEJIANG ACADEMY OF FORESTRY (CN) 2025-06-19 US claimed
WO-2025127642-A1 DIGITAL POLYMERASE CHAIN REACTION-BASED METHOD FOR PROVIDING INFORMATION FOR DIAGNOSING MICROSATELLITE INSTABILITY, AND KIT THEREFOR 주식회사 시선바이오머티리얼스 2025-06-19 WO claimed
US-20250154237-A1 FULLY HUMAN MONOCLONAL ANTIBODIES AGAINST HUMAN PROGRANULIN A & G PHARMACEUTICAL, INC. 2025-05-15 US claimed
WO-2025090061-A1 ULTRASONIC INDICATOR DEVICE AND METHOD FOR MONITORING ULTRASONICATION JP LABORATORIES, INC. (US) 2025-05-01 WO claimed
US-20250115626-A1 BIFUNCTIONAL LINKER COMPRISING METAALLYLSILANE AND METHOD FOR PREPARING SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) 2025-04-10 US claimed
US-5124071-A Microscopic particles containing imbedded fluorescent dyes and use thereof in particle-image velocimetry JOHNS HOPKINS UNIVERSITY, THE 1992-06-23 US claimed
WO-1992006219-A1 IMPROVED NUCLEIC ACID SEQUENCE ANALYSIS WITH NUCLEOSIDE-5'-0-(1-THIOTRIPHOSPHATES) APPLIED BIOSYSTEMS, INC. (US) 1992-04-16 WO claimed
US-5100802-A Fluorescent Dye THE DOW CHEMICAL COMPANY (US) 1992-03-31 US claimed
US-5019496-A Photopolymerization diagnostic test composition and method for immunoassay and nucleic acid assay OSTER GERALD (US) 1991-05-28 US claimed
EP-0383126-A2 Photopolymerization diagnostic test composition and method for immunoassay and nucleic acid assay OSTER, Gerald (US) 1990-08-22 EP claimed
US-4728796-A Method for ionization of polymers MEDICAL COLLEGE OF WISCONSIN (US) 1988-03-01 US claimed
US-4662940-A FLUORESCENT DYES TRI-X CORPORATION (US) 1987-05-05 US claimed
EP-0015767-B1 COMPOSITIONS, METHODS AND ELEMENTS FOR DETECTING OR ASSAYING PEROXIDATIVELY ACTIVE SUBSTANCES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-05-11 EP claimed
US-4269938-A BASED ON THE PEROXIDASE-CATALYZED PEROXIDATION OF DIACETYLDICHLOROFLUORESCIN TO DICHLOROFLUORESCEIN; HIGH SPEED IMMUNOASSAY; STORAGE STABILITY EASTMAN KODAK COMPANY (US) 1981-05-26 US claimed
EP-0015767-A1 Compositions, methods and elements for detecting or assaying peroxidatively active substances EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1980-09-17 EP claimed