Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dichlorofluorescein SCHEMBL157703 | 0.93 | MAPT (0.64) | MAPTMEN1KMT2ATDP1FTO | |
| Dichlorofluorescein SCHEMBL29364373 | 0.93 | MAPT (0.64) | MAPTMEN1KMT2ATDP1FTO | |
| Dichlorofluorescein SCHEMBL30606648 | 0.93 | MAPT (0.64) | MAPTMEN1KMT2ATDP1FTO | |
| Dichlorofluorescein SCHEMBL25207800 | 0.91 | MAPT (0.63) | MAPTMEN1KMT2ATDP1FTO | |
| Dichlorofluorescein SCHEMBL21196869 | 0.89 | MAPT (0.57) | MAPTMEN1KMT2ATDP1FTO | |
| Dichlorofluorescein SCHEMBL28221705 | 0.88 | MAPT (0.59) | MAPTMEN1KMT2ATDP1FTO | |
| SCHEMBL10145452 | 0.86 | MAPT (0.54) | MAPTMEN1KMT2ATDP1FTO | |
| SCHEMBL10176074 | 0.86 | MAPT (0.54) | MAPTMEN1KMT2ATDP1FTO | |
| SCHEMBL4173117 | 0.86 | FTO (0.79) | MAPTMEN1KMT2ATDP1FTO | |
| SCHEMBL29871701 | 0.86 | FTO (0.79) | MAPTMEN1KMT2ATDP1FTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250177-B1 | LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES | VERSITECH LTD (CN) | 2014-06-18 | — | — | EP | disclosed |