Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 5/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.46 |
| ▸ | PRNP | P04156 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775178 | 0.82 | MEN1 (0.44) | LMNAKMT2AMEN1KDM1APTGS1 | |
| SCHEMBL5241327 | 0.82 | CYP1A2 (0.60) | LMNAKMT2AMEN1KDM1APTGS1 | |
| SCHEMBL29376932 | 0.80 | KMT2A (0.52) | LMNAKMT2AMEN1KDM1APTGS1 | |
| SCHEMBL39172 | 0.80 | KMT2A (0.52) | LMNAKMT2AMEN1KDM1APTGS1 | |
| Iodide SCHEMBL11442732 | 0.78 | KMT2A (0.51) | LMNAKMT2AMEN1KDM1APTGS1 | |
| SCHEMBL11277636 | 0.78 | PIM1 (0.60) | LMNAKMT2AMEN1KDM1APIM1 | |
| SCHEMBL9279103 | 0.77 | PIM1 (0.50) | LMNAKMT2AMEN1KDM1APTGS1 | |
| SCHEMBL19076255 | 0.74 | ALDH1A1 (0.53) | LMNAKMT2AMEN1KDM1APTGS1 | |
| SCHEMBL11784508 | 0.74 | BCHE (0.48) | LMNAKMT2AMEN1KDM1APTGS1 | |
| SCHEMBL9257943 | 0.73 | KMT2A (0.44) | LMNAKMT2AMEN1KDM1APTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014086478-A1 | INHIBITORS OF MALT1 PROTEASE | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2014-06-12 | — | — | WO | disclosed |
| WO-2008009935-A1 | PHARMACEUTICAL COMPOSITIONS AND THEIR USE | UCL BUSINESS PLC (GB) | 2008-01-24 | — | — | WO | disclosed |
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | LMNA 4116/4885KMT2A 2263/4885MEN1 3562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.