SCHEMBL15775309

SCHEMBL15775309

CC(C)(C)OC(=O)CN1CCN(CC(=O)OC(C)(C)C)CCN(C(CCC(=O)NCCCOCCOCCOCCCNC(=O)CCC(=O)O)C(=O)OC(C)(C)C)CC1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALB P02768 1/20 0.37
FOLH1 Q04609 5/20 0.35
BCHE P06276 1/20 0.34
ACHE P22303 1/20 0.34
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 2/20 0.33
EPOR P19235 2/20 0.32
TLR2 O60603 1/20 0.32
TLR1 Q15399 1/20 0.32
NTSR1 P30989 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
ITGB3 P05106 2/20 0.31
ITGA2B P08514 2/20 0.31
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27149493 0.91 TLR2 (0.34) ALBFOLH1BCHEACHEKDM4E
SCHEMBL27150933 0.91 TLR2 (0.34) ALBFOLH1BCHEACHEKDM4E
SCHEMBL27150935 0.91 TLR2 (0.34) ALBFOLH1BCHEACHEKDM4E
SCHEMBL27113413 0.91 TLR2 (0.34) ALBFOLH1BCHEACHEKDM4E
SCHEMBL27145364 0.89 TLR2 (0.33) ALBFOLH1BCHEACHEKDM4E
SCHEMBL27145367 0.89 TLR2 (0.33) ALBFOLH1BCHEACHEKDM4E
SCHEMBL31399674 0.88 ALB (0.37) ALBFOLH1BCHEACHEKDM4E
SCHEMBL15775091 0.86 ALDH1A1 (0.42) KDM4EALDH1A1EPORTLR2TLR1
SCHEMBL22076667 0.86 CACNA1H (0.38) ALBBCHEACHEKDM4EALDH1A1
SCHEMBL27113557 0.86 CACNA1H (0.38) ALBBCHEACHEKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078095-A1 NEUROTENSIN RECEPTOR LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2026-03-19 US disclosed
EP-3712131-B1 NEUROTENSIN RECEPTOR LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2023-02-01 EP disclosed
US-10961199-B2 Neurotensin receptor ligands 3B PHARMACEUTICALS GMBH (DE) 2021-03-30 US disclosed
US-20210087149-A1 NEUROTENSIN RECEPTOR LIGANDS 3B Pharmaceuticals (DE) 2021-03-25 US disclosed
US-10799605-B2 Conjugate comprising a neurotensin receptor ligand and use thereof 3B PHARMACEUTICALS GMBH (DE) 2020-10-13 US disclosed
EP-3712131-A1 NEUROTENSIN RECEPTOR LIGANDS 3B Pharmaceuticals GmbH (DE) 2020-09-23 EP disclosed
EP-2928870-B1 NEUROTENSIN RECEPTOR LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2020-04-08 EP disclosed
US-20170119913-A1 CONJUGATE COMPRISING A NEUROTENSIN RECEPTOR LIGAND AND USE THEREOF 3B PHARMACEUTICALS GMBH (DE) 2017-05-04 US disclosed
EP-3154638-A1 CONJUGATE COMPRISING A NEUROTENSIN RECEPTOR LIGAND AND USE THEREOF 3B Pharmaceuticals GmbH (DE) 2017-04-19 EP disclosed
WO-2015188934-A1 CONJUGATE COMPRISING A NEUROTENSIN RECEPTOR LIGAND AND USE THEREOF 3B PHARMACEUTICALS GMBH (DE) 2015-12-17 WO disclosed
EP-2954934-A1 Conjugate comprising a neurotensin receptor ligand and use thereof 3B Pharmaceuticals GmbH (DE) 2015-12-16 EP disclosed
US-20150299133-A1 NEUROTENSIN RECEPTOR LIGANDS 3 B Pharmaceuticals GmbH 2015-10-22 US disclosed
EP-2928870-A1 NEUROTENSIN RECEPTOR LIGANDS 3B Pharmaceuticals GmbH (DE) 2015-10-14 EP disclosed
WO-2014086499-A1 NEUROTENSIN RECEPTOR LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2014-06-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210087149-A1 NEUROTENSIN RECEPTOR LIGANDS NTSR1, NTSR2, TACR3 ALB 2299/4885FOLH1 1350/4885BCHE 1531/4885
US-20150299133-A1 NEUROTENSIN RECEPTOR LIGANDS NTSR1, NTSR2, TACR3 ALB 2298/4885FOLH1 1359/4885BCHE 1520/4885
US-20170119913-A1 CONJUGATE COMPRISING A NEUROTENSIN RECEPTOR LIGAND AND USE THEREOF NTSR1, NTSR2, ADGRF1 ALB 1695/4885FOLH1 500/4885BCHE 1005/4885
US-10799605-B2 Conjugate comprising a neurotensin receptor ligand and use thereof NTSR1, NTSR2, TAAR1 ALB 1524/4885FOLH1 486/4885BCHE 1038/4885
US-10961199-B2 Neurotensin receptor ligands NTSR1, NTSR2, TACR3 ALB 2298/4885FOLH1 1359/4885BCHE 1520/4885
US-20260078095-A1 NEUROTENSIN RECEPTOR LIGANDS NTSR1, NTSR2, GRPR ALB 2968/4885FOLH1 762/4885BCHE 1951/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.