Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 14/20 | 1.00 |
| ▸ | TNKS2 | Q9H2K2 | 13/20 | 1.00 |
| ▸ | GUSB | P08236 | 7/20 | 1.00 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 1.00 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 1.00 |
| ▸ | PARP1 | P09874 | 7/20 | 0.69 |
| ▸ | MMP2 | P08253 | 1/20 | 0.68 |
| ▸ | MMP9 | P14780 | 1/20 | 0.68 |
| ▸ | MMP8 | P22894 | 1/20 | 0.68 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.65 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | WNT3A | P56704 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885282 | 0.86 | TNKS (0.93) | TNKSTNKS2GUSBPARP2NLRP3 | |
| SCHEMBL30665826 | 0.86 | TNKS (0.75) | TNKSTNKS2GUSBPARP2NLRP3 | |
| SCHEMBL873782 | 0.85 | GUSB (1.00) | TNKSTNKS2GUSBPARP2NLRP3 | |
| SCHEMBL2991045 | 0.84 | TNKS (0.73) | TNKSTNKS2GUSBPARP2NLRP3 | |
| SCHEMBL6124189 | 0.83 | TNKS (0.93) | TNKSTNKS2GUSBPARP2NLRP3 | |
| SCHEMBL258433 | 0.83 | TNKS (1.00) | TNKSTNKS2GUSBPARP2NLRP3 | |
| SCHEMBL29592833 | 0.83 | TNKS (1.00) | TNKSTNKS2GUSBPARP2NLRP3 | |
| Hydrochloric Acid SCHEMBL31529601 | 0.81 | TNKS (0.96) | TNKSTNKS2GUSBPARP2NLRP3 | |
| SCHEMBL259520 | 0.81 | TNKS (0.68) | TNKSTNKS2GUSBPARP2NLRP3 | |
| SCHEMBL5010434 | 0.81 | MMP2 (1.00) | TNKSTNKS2GUSBPARP2NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359548-A | Preparation method of benzodiazepine compound | 重庆医科大学 | 2024-07-19 | — | — | CN | disclosed |
| CN-115010671-B | One-step synthesis method of 2-substituted quinazolinone | 江苏大学 | 2023-10-10 | — | — | CN | disclosed |
| CN-111777564-B | Method for synthesizing quinazolinone compound by photocatalytic alcohol oxidation in aqueous phase | 许昌学院 | 2023-07-14 | — | — | CN | disclosed |
| CN-111875549-B | Method for synthesizing quinazolinone compound in aqueous phase through photocatalysis | 许昌学院 | 2023-04-28 | — | — | CN | disclosed |
| CN-115010671-A | One-step synthesis method of 2-substituted quinazolinone | 江苏大学 | 2022-09-06 | — | — | CN | disclosed |
| CN-111777564-A | Method for synthesizing quinazolinone compound through photocatalytic alcohol oxidation in aqueous phase | 许昌学院 | 2020-10-16 | — | — | CN | disclosed |
| CN-104910079-A | Method for preparing 4(3H)-quinazolinone derivative through toluene and derivative oxidation one-pot process | UNIV TONGJI | 2015-09-16 | — | — | CN | disclosed |
| CN-104557738-A | Green synthesis method of 4(3H)-quinazolinone | UNIV HUNAN | 2015-04-29 | — | — | CN | disclosed |
| US-20140256754-A1 | QUINAZOLINES AS B-GLUCURONIDASE NOVEL INHIBITORS | CHOUDHARY MUHAMMAD IQBAL (PK) | 2014-09-11 | — | — | US | disclosed |
| US-20140256754-A1 | QUINAZOLINES AS B-GLUCURONIDASE NOVEL INHIBITORS | CHOUDHARY MUHAMMAD IQBAL (PK) | 2014-09-11 | — | — | US | disclosed |
| US-20140256754-A1 | QUINAZOLINES AS B-GLUCURONIDASE NOVEL INHIBITORS | CHOUDHARY MUHAMMAD IQBAL (PK) | 2014-09-11 | — | — | US | disclosed |
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256754-A1 | QUINAZOLINES AS B-GLUCURONIDASE NOVEL INHIBITORS | GUSB, GBA3, GAA | TNKS 1726/4885TNKS2 1674/4885GUSB 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.