Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 18/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775291 | 0.81 | PPARG (0.52) | BCHEACHEMAPTGAAALDH1A1 | |
| SCHEMBL4776664 | 0.69 | BCHE (1.00) | BCHEACHEMAPT | |
| SCHEMBL15775918 | 0.68 | AR (0.46) | MAPTGAANPSR1ALDH1A1CYP1A2 | |
| SCHEMBL4780247 | 0.68 | BCHE (0.61) | BCHEACHE | |
| SCHEMBL4446747 | 0.68 | BCHE (0.73) | BCHEACHE | |
| SCHEMBL30300504 | 0.68 | BCHE (0.73) | BCHEACHE | |
| SCHEMBL15775420 | 0.68 | BCHE (0.71) | BCHEACHEMAPTGAANPSR1 | |
| SCHEMBL15775275 | 0.68 | MEN1 (0.52) | BCHEACHEMAPTALDH1A1MEN1 | |
| SCHEMBL3808721 | 0.66 | ALDH1A1 (0.52) | BCHEACHEMAPTGAAALDH1A1 | |
| SCHEMBL8739172 | 0.66 | BCHE (0.76) | BCHEACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014086478-A1 | INHIBITORS OF MALT1 PROTEASE | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2014-06-12 | — | — | WO | disclosed |