Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 2/20 | 0.40 |
| ▸ | FNTB | P49356 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775918 | 0.85 | AR (0.46) | PPARGMAPTMAPK1KDM4EMEN1 | |
| SCHEMBL15775174 | 0.82 | PPARG (0.51) | PPARGMAPTMAPK1KDM4EMEN1 | |
| SCHEMBL15775418 | 0.81 | BCHE (0.52) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL15775129 | 0.79 | PPARG (0.47) | PPARGMAPTMAPK1KDM4EMEN1 | |
| SCHEMBL15775209 | 0.78 | PPARG (0.47) | PPARGMAPTMAPK1KDM4EMEN1 | |
| SCHEMBL3240026 | 0.74 | MAPT (0.58) | PPARGMAPTMAPK1KDM4EMEN1 | |
| SCHEMBL15775275 | 0.72 | MEN1 (0.52) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL3808721 | 0.72 | ALDH1A1 (0.52) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL12311066 | 0.70 | MEN1 (0.69) | PPARGMAPTMEN1KMT2ALMNA | |
| SCHEMBL15775293 | 0.70 | MAPK1 (0.82) | PPARGMAPTMAPK1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014086478-A1 | INHIBITORS OF MALT1 PROTEASE | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2014-06-12 | — | — | WO | disclosed |