Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 12/20 | 1.00 |
| ▸ | CTSV | O60911 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775454 | 0.83 | PARP1 (1.00) | PARP1PARP2 | |
| SCHEMBL4859629 | 0.83 | PARP1 (0.71) | PARP1CTSVCTSLGPR84KMT2A | |
| SCHEMBL2532412 | 0.79 | PARP1 (0.65) | PARP1CTSVCTSLGPR84KMT2A | |
| SCHEMBL15775820 | 0.79 | PARP1 (0.64) | PARP1CTSVCTSLGPR84KMT2A | |
| SCHEMBL9540950 | 0.76 | PARP1 (0.61) | PARP1CTSVCTSLGPR84 | |
| SCHEMBL7343701 | 0.74 | LOXL2 (0.60) | PARP1CTSVCTSLGPR84KMT2A | |
| SCHEMBL423379 | 0.72 | PARP1 (1.00) | PARP1 | |
| SCHEMBL5750392 | 0.70 | PARP1 (0.53) | PARP1 | |
| SCHEMBL5747812 | 0.70 | PARP1 (0.53) | PARP1 | |
| SCHEMBL5746985 | 0.70 | PARP1 (0.53) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |