Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.61 |
| ▸ | TNKS | O95271 | 3/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | APLNR | P35414 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343701 | 0.76 | LOXL2 (0.60) | PARP1TNKSCTSVCTSLGPR84 | |
| SCHEMBL4859629 | 0.76 | PARP1 (0.71) | PARP1CTSVCTSLGPR84GHSR | |
| SCHEMBL15775671 | 0.76 | PARP1 (1.00) | PARP1CTSVCTSLGPR84 | |
| SCHEMBL7417773 | 0.75 | MTNR1A (0.60) | PARP1MTNR1AMTNR1BGPR84SLC2A1 | |
| SCHEMBL6643174 | 0.74 | PARP1 (0.44) | PARP1TNKSTNKS2 | |
| SCHEMBL16579025 | 0.73 | TNKS (0.58) | PARP1TNKSTNKS2THRBNQO2 | |
| SCHEMBL6648863 | 0.73 | PARP1 (0.46) | PARP1TNKSTNKS2 | |
| SCHEMBL9539977 | 0.72 | GHSR (0.54) | PARP1TNKS2MTNR1AMTNR1BGPR84 | |
| SCHEMBL15775820 | 0.72 | PARP1 (0.64) | PARP1CTSVCTSLGPR84GHSR | |
| SCHEMBL2532412 | 0.72 | PARP1 (0.65) | PARP1CTSVCTSLGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014086-A1 | SUBSTITUTED 1-ISOQUINOLONE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-07-22 | — | — | WO | disclosed |