Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.56 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | MC3R | P41968 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.43 |
| ▸ | PTGFR | P43088 | 2/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16509907 | 1.00 | ALDH1A1 (0.56) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL2738709 | 1.00 | ALDH1A1 (0.56) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL3439766 | 1.00 | ALDH1A1 (0.56) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL14098071 | 1.00 | ALDH1A1 (0.56) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL12455915 | 1.00 | ALDH1A1 (0.56) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL2738717 | 1.00 | ALDH1A1 (0.56) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL15960983 | 0.99 | ALDH1A1 (0.55) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL10051965 | 0.97 | ALDH1A1 (0.53) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL3439776 | 0.93 | ALDH1A1 (0.52) | ALDH1A1KDM4EHKDC1TDP1SAE1 | |
| SCHEMBL3439786 | 0.93 | ALDH1A1 (0.52) | ALDH1A1KDM4EHKDC1TDP1SAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140235665-A1 | ANTI-CONSTIPATION COMPOSITION | SUCAMPO AG (CH) | 2014-08-21 | — | — | US | disclosed |
| US-20140235665-A1 | ANTI-CONSTIPATION COMPOSITION | SUCAMPO AG (CH) | 2014-08-21 | — | — | US | disclosed |
| US-8748454-B2 | Anti-constipation composition | SUCAMPO AG (CH) | 2014-06-10 | — | — | US | disclosed |
| US-8071613-B2 | Anti-constipation composition | SUCAMPO AG (CH) | 2011-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140235665-A1 | ANTI-CONSTIPATION COMPOSITION | SLC10A2, FABP6, VIP | ALDH1A1 2591/4885KDM4E 3896/4885HKDC1 3090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.