⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4540276 | 0.92 | — | — | |
| SCHEMBL11861174 | 0.90 | DNM1 (0.52) | — | |
| SCHEMBL2932800 | 0.90 | DNM1 (0.52) | — | |
| SCHEMBL32661414 | 0.90 | DNM1 (0.52) | — | |
| SCHEMBL29374911 | 0.90 | DNM1 (0.52) | — | |
| SCHEMBL3501059 | 0.82 | — | — | |
| SCHEMBL7130140 | 0.82 | ALDH1A1 (0.42) | — | |
| SCHEMBL11695184 | 0.78 | ALDH1A1 (0.47) | — | |
| SCHEMBL606730 | 0.74 | TSHR (0.50) | — | |
| SCHEMBL16844219 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4037679-B1 | A PROCESS FOR THE PREPARATION OF HIGHLY PURE VALSARTAN | HARMAN FINOCHEM LTD (IN) | 2025-08-06 | — | — | EP | claimed |
| US-12365654-B2 | Process for the preparation of highly pure valsartan | HARMAN FINOCHEM LIMITED (IN) | 2025-07-22 | — | — | US | claimed |
| CN-119827665-A | Method for detecting related substances in famotidine injection by liquid chromatography-mass spectrometry | 华夏生生药业(北京)有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-119643729-A | Method for detecting content of nitrosamine impurity NMBA in cefepime hydrochloride for injection | 齐鲁制药有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-119246753-A | Universal analysis and detection method for 7 nitrosamines in medicine | 上海合全药物研发有限公司 | 2025-01-03 | — | — | CN | claimed |
| WO-2024192335-A1 | ALTERNATIVE STRATEGIES FOR METHANOBACTIN PRODUCTION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-09-19 | — | — | WO | claimed |
| CN-118090622-A | Photoelectric bimodal chemical sensor for detecting nitrosamine and preparation method thereof | 同济大学 | 2024-05-28 | — | — | CN | claimed |
| CN-118033011-A | Detection method of NMBA in sartan drugs | 珠海润都制药股份有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-113030352-B | Determination and analysis method for NMBA content in irbesartan | 上海奥博生物医药股份有限公司 | 2024-03-22 | — | — | CN | claimed |
| CN-117686599-A | Analysis and detection method for nitrosamine impurities in ticagrelor | 常州制药厂有限公司 | 2024-03-12 | — | — | CN | claimed |
| CN-115963202-A | Method for determining nitrosamine genotoxic impurities by using gas chromatography triple quadrupole mass spectrometry | 上海合全药物研发有限公司 | 2023-04-14 | — | — | CN | claimed |
| US-20230057675-A1 | A PROCESS FOR THE PREPARATION OF HIGHLY PURE VALSARTAN | HARMAN FINOCHEM LIMITED (IN) | 2023-02-23 | — | — | US | claimed |
| CN-115548701-A | Method for obtaining active common mode reflection coefficient of constant-amplitude in-phase excitation loop antenna array | 中国电子科技集团公司第三十八研究所 | 2022-12-30 | — | — | CN | claimed |
| EP-4037679-A1 | A PROCESS FOR THE PREPARATION OF HIGHLY PURE VALSARTAN | Harman Finochem Limited (IN) | 2022-08-10 | — | — | EP | claimed |
| CN-114845713-A | Process for preparing high purity valsartan | 哈曼菲诺化学有限公司 | 2022-08-02 | — | — | CN | claimed |
| CN-114366445-A | Online processing technology for absorption core body | 泉州市美高品牌运营有限公司 | 2022-04-19 | — | — | CN | claimed |
| CN-113899834-B | Method for detecting nitrosamine impurities in medicine | 北京联嘉医药科技开发有限公司 | 2022-04-01 | — | — | CN | claimed |
| CN-112129853-A | Method for detecting nitrosamine impurities in candesartan cilexetil | 天地恒一制药股份有限公司 | 2020-12-25 | — | — | CN | claimed |
| CN-105353068-A | GC-MS/MS assay determination method for volatile N-nitrosamine in tobacco and smokeless tobacco products | ZHENGZHOU TOBACCO RES CNTC | 2016-02-24 | — | — | CN | claimed |
| US-4053317-A | N-NITROSO COMPOUND, PHOTOPOLYMERIZABLE COMPOUND | TEIJIN LIMITED (JA) | 1977-10-11 | — | — | US | claimed |