Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | CCNC | P24863 | 2/20 | 0.47 |
| ▸ | CDK8 | P49336 | 2/20 | 0.47 |
| ▸ | TTK | P33981 | 4/20 | 0.45 |
| ▸ | KIT | P10721 | 4/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15288708 | 0.86 | KCNH2 (0.51) | FFAR1MAP4K4CCNCCDK8TTK | |
| SCHEMBL17608240 | 0.83 | FFAR1 (0.50) | FFAR1MAP4K4CCNCCDK8TTK | |
| SCHEMBL17809694 | 0.82 | LRRK2 (0.45) | TTKLRRK2 | |
| SCHEMBL29718778 | 0.82 | CDK8 (0.51) | FFAR1MAP4K4CCNCCDK8TTK | |
| SCHEMBL20400196 | 0.80 | FFAR1 (0.48) | FFAR1MAP4K4CCNCCDK8TTK | |
| SCHEMBL15200528 | 0.79 | FFAR1 (0.53) | FFAR1MAP4K4TTKALOX5APPDK2 | |
| SCHEMBL17809809 | 0.78 | LRRK2 (0.64) | LRRK2PIM1 | |
| SCHEMBL15262270 | 0.77 | FFAR1 (0.51) | FFAR1MAP4K4CCNCCDK8TTK | |
| SCHEMBL10195600 | 0.77 | NAMPT (0.49) | MAP4K4KITPDK2LRRK2 | |
| SCHEMBL15299283 | 0.77 | FFAR1 (0.74) | FFAR1MAP4K4CCNCCDK8TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9597310-B2 | Indanyloxydihydrobenzofuranylacetic acids | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-03-21 | — | — | US | disclosed |
| US-20160235706-A1 | INDANYLOXYDIHYDROBENZOFURANYLACETIC ACIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-08-18 | — | — | US | disclosed |
| US-20140163025-A1 | INDANYLOXYDIHYDROBENZOFURANYLACETIC ACIDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140163025-A1 | INDANYLOXYDIHYDROBENZOFURANYLACETIC ACIDS | GPR119, GPBAR1, GPR52 | FFAR1 6/4885MAP4K4 2779/4885CCNC 3447/4885 |
| US-20160235706-A1 | INDANYLOXYDIHYDROBENZOFURANYLACETIC ACIDS | GPR119, GPBAR1, GPR52 | FFAR1 6/4885MAP4K4 2779/4885CCNC 3447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.