Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17879719 | 0.80 | BRD4 (0.44) | MAPK1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL15788370 | 0.78 | ALDH1A1 (0.48) | KMT2AALDH1A1KDM4EGAAHPGD | |
| SCHEMBL6803759 | 0.75 | ESR1 (0.49) | MAPK1ALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL17517333 | 0.73 | ALDH1A1 (0.41) | MAPK1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL15788368 | 0.73 | KMT2A (0.38) | MAPK1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL13295979 | 0.73 | ALDH1A1 (0.46) | KMT2AALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL7873755 | 0.72 | ESR1 (0.44) | MAPK1ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL17879720 | 0.71 | BRD4 (0.56) | MAPK1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7881193 | 0.70 | KMT2A (0.54) | KMT2AALDH1A1KDM4EGAAHPGD | |
| SCHEMBL27389398 | 0.70 | ESR1 (0.45) | MAPK1ALDH1A1KDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158039-A1 | BROMODOMAIN INHIBITORS | ABBVIE INC (US) | 2023-05-25 | — | — | US | disclosed |
| US-20160143916-A1 | BROMODOMAIN INHIBITORS | ABBVIE INC (US) | 2016-05-26 | — | — | US | disclosed |
| US-9296741-B2 | Bromodomain inhibitors | ABBVIE INC. (US) | 2016-03-29 | — | — | US | disclosed |
| US-20140162971-A1 | BROMODOMAIN INHIBITORS | ABBVIE INC. | 2014-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140162971-A1 | BROMODOMAIN INHIBITORS | BRD4, BRD1, BRD3 | MAPK1 343/4885KMT2A 405/4885ALDH1A1 1794/4885 |
| US-20230158039-A1 | BROMODOMAIN INHIBITORS | BRD4, BRD1, BRD3 | MAPK1 343/4885KMT2A 405/4885ALDH1A1 1794/4885 |
| US-20160143916-A1 | BROMODOMAIN INHIBITORS | BRD4, BRD1, BRD3 | MAPK1 343/4885KMT2A 405/4885ALDH1A1 1794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.