Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.56 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.56 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.56 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.56 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.56 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.56 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.56 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.55 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.54 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.54 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.53 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.53 |
| ▸ | GPR17 | Q13304 | 2/20 | 0.52 |
| ▸ | DTYMK | P23919 | 2/20 | 0.52 |
| ▸ | PNP | P00491 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17117823 | 0.91 | NT5E (0.67) | NT5EPOLBENPP1P2RY1P2RY6 | |
| SCHEMBL29642033 | 0.91 | NT5E (0.64) | NT5EPOLBENPP1P2RY1P2RY6 | |
| SCHEMBL12932286 | 0.91 | NT5E (0.67) | NT5EPOLBENPP1P2RY1P2RY6 | |
| SCHEMBL4820794 | 0.91 | NT5E (0.67) | NT5EPOLBENPP1P2RY1P2RY6 | |
| SCHEMBL345288 | 0.91 | NT5E (0.67) | NT5EPOLBENPP1P2RY1P2RY6 | |
| SCHEMBL29400356 | 0.91 | NT5E (0.67) | NT5EPOLBENPP1P2RY1P2RY6 | |
| SCHEMBL15573313 | 0.91 | NT5E (0.64) | NT5EPOLBENPP1P2RY1P2RY6 | |
| SCHEMBL15794369 | 0.89 | NT5E (0.62) | NT5EPOLBENPP1P2RY1P2RY6 | |
| SCHEMBL21056508 | 0.89 | NT5E (0.62) | NT5EPOLBENPP1P2RY1P2RY6 | |
| 2-Chlorodeoxyadenosine Triphosphate SCHEMBL1064481 | 0.89 | NT5E (0.78) | NT5EPOLBENPP1P2RY1P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140170689-A1 | Modified Diguanylate Cyclase-Phosphodiesterase and Method for Enzymatic Production of Cyclic-diGMP | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-06-19 | — | — | US | claimed |
| US-20140170689-A1 | Modified Diguanylate Cyclase-Phosphodiesterase and Method for Enzymatic Production of Cyclic-diGMP | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-06-19 | — | — | US | disclosed |