SCHEMBL29642033

SCHEMBL29642033

Nc1nc(O)nc2c1ncn2[C@H]1C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NT5E P21589 1/20 0.64
▸ POLB P06746 2/20 0.63
▸ P2RY1 P47900 5/20 0.58
▸ ENPP1 P22413 4/20 0.58
▸ P2RY6 Q15077 2/20 0.58
▸ P2RX1 P51575 2/20 0.58
▸ P2RX3 P56373 2/20 0.58
▸ P2RY11 Q96G91 1/20 0.58
▸ P2RX4 Q99571 1/20 0.58
▸ P2RY12 Q9H244 1/20 0.56
▸ P2RY2 P41231 1/20 0.56
▸ P2RY4 P51582 1/20 0.56
▸ RNASEL Q05823 1/20 0.55
▸ P2RX2 Q9UBL9 1/20 0.54
▸ GPR17 Q13304 2/20 0.53
▸ PNP P00491 1/20 0.53
▸ LMNA P02545 1/20 0.53
▸ TP53 P04637 1/20 0.53
▸ HTT P42858 1/20 0.53
▸ PDE4D Q08499 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15573313 1.00 NT5E (0.64) NT5EPOLBP2RY1ENPP1P2RY6
SCHEMBL21056508 0.93 NT5E (0.62) NT5EPOLBP2RY1ENPP1P2RY6
SCHEMBL12932286 0.93 NT5E (0.67) NT5EPOLBP2RY1ENPP1P2RY6
SCHEMBL17117823 0.93 NT5E (0.67) NT5EPOLBP2RY1ENPP1P2RY6
SCHEMBL345288 0.93 NT5E (0.67) NT5EPOLBP2RY1ENPP1P2RY6
SCHEMBL4820794 0.93 NT5E (0.67) NT5EPOLBP2RY1ENPP1P2RY6
SCHEMBL29400356 0.93 NT5E (0.67) NT5EPOLBP2RY1ENPP1P2RY6
SCHEMBL15793736 0.91 NT5E (0.62) NT5EPOLBP2RY1ENPP1P2RY6
2-Chlorodeoxyadenosine Triphosphate SCHEMBL1064487 0.91 NT5E (0.78) NT5EPOLBP2RY1ENPP1P2RY6
2-Chlorodeoxyadenosine Triphosphate SCHEMBL1064481 0.91 NT5E (0.78) NT5EPOLBP2RY1ENPP1P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023081883-A2 METHYLATION SEQUENCING METHODS AND COMPOSITIONS ULTIMA GENOMICS, INC. (US) 2023-05-11 — — WO claimed
US-20260120804-A1 SEQUENCING ALGORITHM ILLUMINA SINGAPORE PTE LTD (SG) 2026-04-30 — — US disclosed
EP-4640847-A2 METHOD FOR PREFERENTIALLY AMPLIFYING NUCLEIC ACID MOLECULES LONGER THAN 1 KBP Illumina Singapore Pte. Ltd. (SG) 2025-10-29 — — EP disclosed
EP-4008792-B1 METHOD FOR INTRODUCING MUTATIONS ILLUMINA SINGAPORE PTE LTD (SG) 2025-08-06 — — EP disclosed
US-20250137000-A1 METHODS OF PREFERENTIALLY AMPLIFYING NUCLEIC ACID MOLECULES ILLUMINA SINGAPORE PTE LTD (SG) 2025-05-01 — — US disclosed
US-12203076-B2 Method for introducing mutations ILLUMINA SINGAPORE PTE. LTD. (SG) 2025-01-21 — — US disclosed
EP-4293123-A2 SEQUENCING ALGORITHM Illumina Singapore PTE. Ltd. (SG) 2023-12-20 — — EP disclosed
EP-3950958-B1 SEQUENCING ALGORITHM ILLUMINA SINGAPORE PTE LTD (SG) 2023-10-04 — — EP disclosed
WO-2023081883-A2 METHYLATION SEQUENCING METHODS AND COMPOSITIONS ULTIMA GENOMICS, INC. (US) 2023-05-11 — — WO disclosed
US-20220348940-A1 METHOD FOR INTRODUCING MUTATIONS ILLUMINA SINGAPORE PTE. LTD. (SG) 2022-11-03 — — US disclosed
US-11421238-B2 Method for introducing mutations Longas Technologies Pty Ltd (AU) 2022-08-23 — — US disclosed
EP-4008792-A1 METHOD FOR INTRODUCING MUTATIONS Longas Technologies Pty Ltd (AU) 2022-06-08 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260120804-A1 SEQUENCING ALGORITHM DNMT3A, UPF1, RNMT NT5E 74/4885POLB 14/4885P2RY1 3080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback