Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | POLA1 | P09884 | 1/20 | 0.38 |
| ▸ | POLD1 | P28340 | 1/20 | 0.38 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.33 |
| ▸ | TK1 | P04183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15799931 | 0.98 | POLB (0.39) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL18269460 | 0.95 | TK1 (0.33) | POLBPOLA1POLD1TK1 | |
| SCHEMBL16805874 | 0.94 | POLB (0.36) | POLBPOLA1POLD1TK1 | |
| SCHEMBL20088483 | 0.94 | TK1 (0.33) | POLBPOLA1POLD1TK1 | |
| SCHEMBL17636634 | 0.93 | POLB (0.37) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL15728355 | 0.93 | POLB (0.37) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL13891877 | 0.93 | POLB (0.35) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL17227503 | 0.93 | POLB (0.35) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL20094496 | 0.92 | POLB (0.31) | POLBPOLA1POLD1TK1 | |
| SCHEMBL16809142 | 0.92 | POLB (0.32) | POLBPOLA1POLD1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9222131-B2 | Rhodamine compounds and their use as fluorescent labels | ILLUMINA CAMBRIDGE LIMITED | 2015-12-29 | — | — | US | disclosed |
| US-9222131-B2 | Rhodamine compounds and their use as fluorescent labels | ILLUMINA CAMBRIDGE LIMITED | 2015-12-29 | — | — | US | disclosed |
| US-8993784-B2 | Polymethine compounds and their use as fluorescent labels | ILLUMINA CAMBRIDGE LIMITED (GB) | 2015-03-31 | — | — | US | disclosed |
| US-20140322713-A1 | POLYMETHINE COMPOUNDS AND THEIR USE AS FLUORESCENT LABELS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2014-10-30 | — | — | US | disclosed |
| US-20140255917-A1 | POLYMETHINE COMPOUNDS AND THEIR USE AS FLUORESCENT LABELS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2014-09-11 | — | — | US | disclosed |
| US-20140255917-A1 | POLYMETHINE COMPOUNDS AND THEIR USE AS FLUORESCENT LABELS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2014-09-11 | — | — | US | disclosed |
| US-20140255920-A1 | RHODAMINE COMPOUNDS AND THEIR USE AS FLUORESCENT LABELS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2014-09-11 | — | — | US | disclosed |
| US-20140255920-A1 | RHODAMINE COMPOUNDS AND THEIR USE AS FLUORESCENT LABELS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2014-09-11 | — | — | US | disclosed |
| US-8809551-B1 | Polymethine compounds and their use as fluorescent labels | ILLUMINA CAMBRIDGE LIMITED (GB) | 2014-08-19 | — | — | US | disclosed |
| US-8809551-B1 | Polymethine compounds and their use as fluorescent labels | ILLUMINA CAMBRIDGE LIMITED (GB) | 2014-08-19 | — | — | US | disclosed |
| US-8754244-B1 | Rhodamine compounds and their use as fluorescent labels | ILLUMINA CAMBRIDGE LIMITED (GB) | 2014-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140322713-A1 | POLYMETHINE COMPOUNDS AND THEIR USE AS FLUORESCENT LABELS | POLRMT, FBL, POLM | POLB 15/4885POLA1 171/4885POLD1 153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.