Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049342 | 0.98 | MEN1 (0.37) | MEN1KMT2A | |
| SCHEMBL6304702 | 0.94 | — | — | |
| SCHEMBL3590384 | 0.79 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL11478949 | 0.77 | ALDH1A1 (0.36) | MEN1KMT2A | |
| SCHEMBL27267112 | 0.73 | CHRM2 (0.37) | MEN1KMT2A | |
| SCHEMBL14230806 | 0.72 | — | — | |
| SCHEMBL11477914 | 0.72 | ALDH1A1 (0.31) | — | |
| SCHEMBL12224195 | 0.71 | — | — | |
| SCHEMBL11566720 | 0.71 | — | — | |
| SCHEMBL2111705 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8642802-B2 | Process for the preparation of halogenated benzoic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 2014-02-04 | — | — | US | disclosed |
| EP-2310349-B1 | PROCESS FOR THE PREPARATION OF HALOGENATED BENZOIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2013-04-24 | — | — | EP | disclosed |
| US-20120330055-A1 | PROCESS FOR THE PREPARATION OF HALOGENATED BENZOIC ACID DERIVATIVES | BACHMANN STEPHAN (CH) | 2012-12-27 | — | — | US | disclosed |
| US-8329939-B2 | Process for the preparation of halogenated benzoic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 2012-12-11 | — | — | US | disclosed |
| US-20120130121-A1 | PROCESS FOR THE PREPARATION OF HALOGENATED BENZOIC ACID DERIVATIVES | BACHMANN STEPHAN (CH) | 2012-05-24 | — | — | US | disclosed |
| EP-2310349-A1 | PROCESS FOR THE PREPARATION OF HALOGENATED BENZOIC ACID DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2011-04-20 | — | — | EP | disclosed |
| WO-2009147068-A1 | PROCESS FOR THE PREPARATION OF HALOGENATED BENZOIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-12-10 | — | — | WO | disclosed |
| US-20090306423-A1 | PROCESS FOR THE PREPARATION OF HALOGENATED BENZOIC ACID DERIVATIVES | HOFFMANN-LA ROCHE, INC. | 2009-12-10 | — | — | US | disclosed |
| US-6942966-B1 | libraries formed by permutations; combinatorial chemistry; drug screening | ISIS PHARMACEUTICALS, INC. (US) | 2005-09-13 | — | — | US | disclosed |
| US-6828427-B1 | Oligomeric aminodiol-containing compounds, libraries thereof, and process of preparing the same | ISIS PHARMACEUTICALS, INC. | 2004-12-07 | — | — | US | disclosed |
| EP-0865439-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1998-09-23 | — | — | EP | disclosed |
| WO-1998010286-A1 | METHODS FOR PROCESSING CHEMICAL COMPOUNDS HAVING REACTIVE FUNCTIONAL GROUPS | ISIS PHARMACEUTICALS, INC. (US) | 1998-03-12 | — | — | WO | disclosed |
| EP-0817787-A1 | NITROGENOUS MACROCYCLIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 1998-01-14 | — | — | EP | disclosed |
| WO-1996040672-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| WO-1996030377-A1 | NITROGENOUS MACROCYCLIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 1996-10-03 | — | — | WO | disclosed |
| US-4404082-A | Bipolar electrode for anodic processes in undivided cells | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-09-13 | — | — | US | disclosed |
| EP-0006177-A1 | Bipolar electrode for electrochemical oxidation in diaphragmless cells and its utilisation | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-01-09 | — | — | EP | disclosed |
| US-4149941-A | ELECTROLYTIC ALKOXYLATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-04-17 | — | — | US | disclosed |
| US-4123434-A | Process for preparing trimeric Δ1 -piperideins and trimeric 1-pyrroline | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-31 | — | — | US | disclosed |
| US-4118500-A | Fungicidal alkoxy mono- and dialkoxy N-substituted cyclic amines | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306423-A1 | PROCESS FOR THE PREPARATION OF HALOGENATED BENZOIC ACID DERIVATIVES | CYP2F1, CYP3A5, GABRA5 | MEN1 2937/4885KMT2A 887/4885 |
| US-20120330055-A1 | PROCESS FOR THE PREPARATION OF HALOGENATED BENZOIC ACID DERIVATIVES | CYP2F1, GABRA5, CYP3A5 | MEN1 2863/4885KMT2A 904/4885 |
| US-20120130121-A1 | PROCESS FOR THE PREPARATION OF HALOGENATED BENZOIC ACID DERIVATIVES | CYP2F1, GABRA5, CYP3A5 | MEN1 2863/4885KMT2A 904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.