Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25490750 | 0.74 | ALDH1A1 (0.38) | KDM4EMAPTLMNASMN1; SMN2TSHR | |
| SCHEMBL22873179 | 0.74 | MAOA (0.44) | MAOAMAOBKDM4EHTTSMN1; SMN2 | |
| SCHEMBL29625840 | 0.74 | MAOA (0.43) | MAOAMAOBKDM4EMAPTHTT | |
| SCHEMBL4678872 | 0.74 | MAOA (0.43) | MAOAMAOBKDM4EMAPTHTT | |
| SCHEMBL15596371 | 0.72 | GSTP1 (0.31) | HTT | |
| SCHEMBL20751614 | 0.71 | MAOA (0.39) | MAOAMAOBKDM4ELMNAHTT | |
| SCHEMBL9715725 | 0.71 | KDM4E (0.54) | KDM4EMAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL19789603 | 0.71 | ALDH1A1 (0.39) | MAOAMAOBKDM4EMAPTLMNA | |
| SCHEMBL5965069 | 0.71 | MAOA (0.44) | MAOAMAOBHTTSMN1; SMN2TSHR | |
| SCHEMBL17228466 | 0.70 | MAOA (0.36) | MAOAMAOBKDM4EHPGDERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014090372-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2014-06-19 | — | — | WO | disclosed |