⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclooctane SCHEMBL2204516 | 1.00 | TSHR (0.50) | — | |
| Cyclohexane SCHEMBL3191478 | 1.00 | TSHR (0.50) | — | |
| Cyclopentane SCHEMBL959166 | 1.00 | — | — | |
| Cyclohexane SCHEMBL254050 | 1.00 | — | — | |
| Methyl Alcohol SCHEMBL7653457 | 1.00 | TSHR (0.50) | — | |
| Cycloheptane SCHEMBL2652378 | 1.00 | — | — | |
| Cyclohexane SCHEMBL9165359 | 1.00 | TSHR (0.50) | — | |
| Cyclopropane SCHEMBL1024012 | 1.00 | — | — | |
| Methyl Alcohol SCHEMBL1223378 | 1.00 | TSHR (0.50) | — | |
| Cyclohexane SCHEMBL9632064 | 1.00 | TSHR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128575-A1 | Traction fluid composition | GEIGER RENE | 2006-06-15 | — | — | US | claimed |
| WO-2004061057-A1 | TRACTION FLUID COMPOSITION | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-07-22 | — | — | WO | claimed |
| US-20250270171-A1 | HUMAN PLASMA KALLIKREIN INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2025-08-28 | — | — | US | disclosed |
| US-20250257040-A1 | HUMAN PLASMA KALLIKREIN INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2025-08-14 | — | — | US | disclosed |
| EP-4180424-B1 | SUBSTITUTED PYRAZOLES AS HUMAN PLASMA KALLIKREIN INHIBITORS | BIOCRYST PHARM INC (US) | 2025-06-25 | — | — | EP | disclosed |
| US-12162838-B2 | Human plasma kallikrein inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2024-12-10 | — | — | US | disclosed |
| US-12116346-B2 | Human plasma kallikrein inhibitors | BIOCRYST PHARMACEUTICALS, INC. (US) | 2024-10-15 | — | — | US | disclosed |
| US-20240319597-A1 | RADIATION-SENSITIVE RESIN COMPOSITION, PATTERN FORMATION METHOD, METHOD FOR MANUFACTURING SUBSTRATE, AND COMPOUND | JSR CORPORATION (JP) | 2024-09-26 | — | — | US | disclosed |
| CN-113307772-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2024-06-28 | — | — | CN | disclosed |
| US-20240150296-A1 | HUMAN PLASMA KALLIKREIN INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2024-05-09 | — | — | US | disclosed |
| US-20240150295-A1 | HUMAN PLASMA KALLIKREIN INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2024-05-09 | — | — | US | disclosed |
| US-20010031745-A1 | Antiviral purine derivatives | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2001-10-18 | — | — | US | disclosed |
| EP-1117669-A1 | ANTIVIRAL PURINE DERIVATIVES | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LTD. (GB) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000018775-A1 | ANTIVIRAL PURINE DERIVATIVES | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2000-04-06 | — | — | WO | disclosed |
| US-5916986-A | Coating composition for coatings resistant to environmental etch | BASF CORPORATION (US) | 1999-06-29 | — | — | US | disclosed |
| US-5635302-A | CURED COATING COMPRISING STERICALLY HINDERED MONOMER AND ETHYLENICALLY UNSATURATED COMONOMER | BASF CORPORATION (US) | 1997-06-03 | — | — | US | disclosed |
| CN-1147813-A | Novel compounds, their synthesis and therapeutic use | GILEAD SCIENCES INC (US) | 1997-04-16 | — | — | CN | disclosed |
| US-5098926-A | Antitumor agents | UNIVERSITY PATENTS, INC. (US) | 1992-03-24 | — | — | US | disclosed |
| US-4888341-A | 6-substituted mitomycin analogs | UNIVERSITY PATENTS, INC. (US) | 1989-12-19 | — | — | US | disclosed |
| US-4220795-A | MODIFIERS OF SMOOTH MUSCLE ACTIVITY, PLATELET ANTIAGGREGATING AGENTS, GASTRIC ANTISCRETORY AGENTS, BRONCHODILATORS | MILES LABORATORIES, INC. (US) | 1980-09-02 | — | — | US | disclosed |