⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclooctane SCHEMBL2204516 | 1.00 | TSHR (0.50) | — | |
| Cyclohexane SCHEMBL3191478 | 1.00 | TSHR (0.50) | — | |
| Cyclopentane SCHEMBL959166 | 1.00 | — | — | |
| Cyclohexane SCHEMBL254050 | 1.00 | — | — | |
| Methyl Alcohol SCHEMBL7653457 | 1.00 | TSHR (0.50) | — | |
| Methyl Alcohol SCHEMBL1581201 | 1.00 | — | — | |
| Cyclohexane SCHEMBL9165359 | 1.00 | TSHR (0.50) | — | |
| Cyclopropane SCHEMBL1024012 | 1.00 | — | — | |
| Methyl Alcohol SCHEMBL1223378 | 1.00 | TSHR (0.50) | — | |
| Cyclohexane SCHEMBL9632064 | 1.00 | TSHR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6319310-B1 | FOR ACOUSTIC INK JET PRINTING; TRANSPARENCY, GLOSS, CREASE RESISTANCE | XEROX CORPORATION | 2001-11-20 | — | — | US | claimed |
| US-5922117-A | Ink compositions containing alcohols | XEROX CORPORATION (US) | 1999-07-13 | — | — | US | claimed |
| CN-108398740-A | A kind of phase difference film and its preparation method and application | 江苏创拓新材料有限公司 | 2018-08-14 | — | — | CN | disclosed |
| EP-1349856-B1 | ISOINDOLIN-1-ONE GLUCOKINASE ACTIVATORS | HOFFMANN LA ROCHE (CH) | 2005-06-15 | — | — | EP | disclosed |
| EP-1349856-A2 | ISOINDOLIN-1-ONE GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-10-08 | — | — | EP | disclosed |
| US-6482951-B2 | ISOINDOLIN-1-ONE-SUBSTITUTED PROPIONAMIDE GLUCOKINASE ACTIVATORS WHICH INCREASE INSULIN SECRETION IN THE TREATMENT OF TYPE II DIABETES | HOFFMANN-LA ROCHE INC. | 2002-11-19 | — | — | US | disclosed |
| US-20020082260-A1 | Isoindolin-1-one glucokinase activators | GUERTIN KEVIN RICHARD (US) | 2002-06-27 | — | — | US | disclosed |
| WO-2002048106-A2 | ISOINDOLIN-1-ONE GLUCOKINASE ACTIVATORS | F. HOFFMANN-LA-ROCHE AG (CH) | 2002-06-20 | — | — | WO | disclosed |
| CN-1347693-A | Novel compounds, their synthesis and therapeutic use | GILEAD SCIENCES INC (US) | 2002-05-08 | — | — | CN | disclosed |
| US-6334890-B1 | COMPOSITION COMPRISED OF OXAZOLINE COMPOUND WITH SPECIFIED MELTING POINT AND ACOUSTIC LOSS VALUE, LONG CHAIN CARBAMATE, ALCOHOL COMPOUND, LIGHTFASTNESS COMPONENT, LIGHTFASTNESS ANTIOXIDANT, COLORANT | XEROX CORPORATION | 2002-01-01 | — | — | US | disclosed |
| US-6319310-B1 | FOR ACOUSTIC INK JET PRINTING; TRANSPARENCY, GLOSS, CREASE RESISTANCE | XEROX CORPORATION | 2001-11-20 | — | — | US | disclosed |
| CN-1272105-A | Compound containing six-membered rings, processes for their preparation, and their use as medicaments | GILEAD SCIENCES INC (US) | 2000-11-01 | — | — | CN | disclosed |
| US-6132499-A | Inks | XEROX CORPORATION (US) | 2000-10-17 | — | — | US | disclosed |
| US-6110265-A | Ink compositions | XEROX CORPORATION (US) | 2000-08-29 | — | — | US | disclosed |
| US-6106601-A | MIXTURE CONTAINING OXAZOLINE AND THIOUREA COMPOUNDS | XEROX CORPORATION (US) | 2000-08-22 | — | — | US | disclosed |
| US-6071333-A | Ink compositions | XEROX CORPORATION (US) | 2000-06-06 | — | — | US | disclosed |
| US-6066200-A | COMPRISING A SOLID UREA COMPOUND, AN ALCOHOL, A LIGHTFASTNESS COMPONENT, A LIGHTFAST ANTIOXIDANT, AND A COLORANT | XEROX CORPORATION (US) | 2000-05-23 | — | — | US | disclosed |
| US-5922117-A | Ink compositions containing alcohols | XEROX CORPORATION (US) | 1999-07-13 | — | — | US | disclosed |
| US-5916986-A | Coating composition for coatings resistant to environmental etch | BASF CORPORATION (US) | 1999-06-29 | — | — | US | disclosed |
| US-5635302-A | CURED COATING COMPRISING STERICALLY HINDERED MONOMER AND ETHYLENICALLY UNSATURATED COMONOMER | BASF CORPORATION (US) | 1997-06-03 | — | — | US | disclosed |