SCHEMBL15814701

SCHEMBL15814701

O=C(C(=O)C1(O)C=CC=CC1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CES2 O00748 13/20 0.42
CES1 P23141 12/20 0.42
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
ALDH1A1 P00352 2/20 0.33
DAO P14920 1/20 0.33
TSHR P16473 1/20 0.33
NAPRT Q6XQN6 1/20 0.33
MAPK1 P28482 2/20 0.33
RAB9A P51151 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
XBP1 P17861 1/20 0.33
ATM Q13315 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TRPA1 O75762 1/20 0.32
GSK3B P49841 1/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL534047 0.83 LMNA (0.38) CES2CES1CA2CA4ALDH1A1
SCHEMBL7781547 0.76
SCHEMBL10456255 0.72 CES1 (0.41) CES2CES1ALDH1A1TSHRMAPK1
SCHEMBL18599190 0.72
SCHEMBL809925 0.72
SCHEMBL29144461 0.71 LMNA (0.43) CES2CES1ALDH1A1MAPK1LMNA
SCHEMBL29134044 0.70 CYP11B1 (0.34) ALDH1A1TSHRMAPTSMN1; SMN2
SCHEMBL466305 0.69
SCHEMBL7165670 0.69 LMNA (0.38) CES2CES1CA2CA4ALDH1A1
SCHEMBL28341340 0.68 CA1 (0.38) CES2CA2CA4ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2935397-A1 INTERFACIAL PROCESSES FOR PREPARING PHOTOACTIVE ADDITIVES SABIC Global Technologies B.V. (NL) 2015-10-28 EP disclosed
US-20150259472-A1 INTERFACIAL PROCESSES FOR PREPARING PHOTOACTIVE ADDITIVES SABIC GLOBAL TECHNOLOGIES B.V. 2015-09-17 US disclosed
US-9045590-B2 Interfacial processes for preparing photoactive additives SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-06-02 US disclosed
WO-2014100635-A1 INTERFACIAL PROCESSES FOR PREPARING PHOTOACTIVE ADDITIVES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-06-26 WO disclosed
US-20140179891-A1 INTERFACIAL PROCESSES FOR PREPARING PHOTOACTIVE ADDITIVES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-06-26 US disclosed