Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.96 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.96 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.96 |
| ▸ | APP | P05067 | 1/20 | 0.96 |
| ▸ | THRB | P10828 | 1/20 | 0.96 |
| ▸ | RECQL | P46063 | 1/20 | 0.96 |
| ▸ | BLM | P54132 | 1/20 | 0.96 |
| ▸ | BLVRB | P30043 | 2/20 | 0.82 |
| ▸ | PDE4A | P27815 | 1/20 | 0.82 |
| ▸ | KDR | P35968 | 1/20 | 0.82 |
| ▸ | HTT | P42858 | 1/20 | 0.82 |
| ▸ | PHLPP2 | Q6ZVD8 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chrysamine G SCHEMBL7706038 | 0.98 | MEN1 (1.00) | MEN1KMT2ATDP1APPTHRB | |
| Chrysamine G SCHEMBL7706036 | 0.98 | MEN1 (1.00) | MEN1KMT2ATDP1APPTHRB | |
| Chrysamine G SCHEMBL15818025 | 0.96 | MEN1 (0.96) | MEN1KMT2ATDP1APPTHRB | |
| SCHEMBL7711257 | 0.93 | MEN1 (0.90) | MEN1KMT2ATDP1APPTHRB | |
| SCHEMBL7711260 | 0.93 | MEN1 (0.90) | MEN1KMT2ATDP1APPTHRB | |
| Olsalazine SCHEMBL29769 | 0.93 | MEN1 (0.96) | MEN1KMT2ATDP1APPTHRB | |
| Olsalazine SCHEMBL19693100 | 0.93 | MEN1 (0.96) | MEN1KMT2ATDP1APPTHRB | |
| Olsalazine SCHEMBL2228872 | 0.93 | MEN1 (0.96) | MEN1KMT2ATDP1APPTHRB | |
| Olsalazine SCHEMBL25118 | 0.91 | MEN1 (1.00) | MEN1KMT2ATDP1APPTHRB | |
| Olsalazine SCHEMBL29378994 | 0.91 | MEN1 (1.00) | MEN1KMT2ATDP1APPTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9808155-B2 | Apparatus to detect amyloid in a patient user's retina in a diagnosis, advancement and prognosis of alzheimer's disease, traumatic brain injury, macular degeneration and a plurality of neurodegenerative disorders and ocular diseases | NEUROVISION IMAGING LLC (US) | 2017-11-07 | — | — | US | claimed |
| US-20140176908-A1 | APPARATUS AND METHOD FOR DETECTING AMYLOID IN A RETINA IN A DIAGNOSIS, ADVANCEMENT, AND PROGNOSING OF ALZHEIMER'S DISEASE, TRAUMATIC BRAIN INJURY, MACULAR DEGENERATION AND A PLURALITY OF NEURODEGENERATIVE DISSORDERS AND OCULAR DISEASES | WILDCAT PARTNER HOLDINGS, LP | 2014-06-26 | — | — | US | claimed |
| US-9808155-B2 | Apparatus to detect amyloid in a patient user's retina in a diagnosis, advancement and prognosis of alzheimer's disease, traumatic brain injury, macular degeneration and a plurality of neurodegenerative disorders and ocular diseases | NEUROVISION IMAGING LLC (US) | 2017-11-07 | — | — | US | disclosed |
| US-20140176908-A1 | APPARATUS AND METHOD FOR DETECTING AMYLOID IN A RETINA IN A DIAGNOSIS, ADVANCEMENT, AND PROGNOSING OF ALZHEIMER'S DISEASE, TRAUMATIC BRAIN INJURY, MACULAR DEGENERATION AND A PLURALITY OF NEURODEGENERATIVE DISSORDERS AND OCULAR DISEASES | WILDCAT PARTNER HOLDINGS, LP | 2014-06-26 | — | — | US | disclosed |