Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | APP | P05067 | 1/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | BLVRB | P30043 | 2/20 | 0.85 |
| ▸ | PDE4A | P27815 | 1/20 | 0.85 |
| ▸ | KDR | P35968 | 1/20 | 0.85 |
| ▸ | HTT | P42858 | 1/20 | 0.85 |
| ▸ | PHLPP2 | Q6ZVD8 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chrysamine G SCHEMBL7706038 | 1.00 | MEN1 (1.00) | MEN1KMT2ATDP1APPTHRB | |
| Chrysamine G SCHEMBL15818025 | 0.98 | MEN1 (0.96) | MEN1KMT2ATDP1APPTHRB | |
| Chrysamine G SCHEMBL15818022 | 0.98 | MEN1 (0.96) | MEN1KMT2ATDP1APPTHRB | |
| SCHEMBL7711257 | 0.95 | MEN1 (0.90) | MEN1KMT2ATDP1APPTHRB | |
| SCHEMBL7711260 | 0.95 | MEN1 (0.90) | MEN1KMT2ATDP1APPTHRB | |
| Olsalazine SCHEMBL25118 | 0.92 | MEN1 (1.00) | MEN1KMT2ATDP1APPTHRB | |
| Olsalazine SCHEMBL29861404 | 0.92 | MEN1 (1.00) | MEN1KMT2ATDP1APPTHRB | |
| Olsalazine SCHEMBL29385751 | 0.92 | MEN1 (1.00) | MEN1KMT2ATDP1APPTHRB | |
| Olsalazine SCHEMBL29378994 | 0.92 | MEN1 (1.00) | MEN1KMT2ATDP1APPTHRB | |
| Olsalazine SCHEMBL25119 | 0.92 | MEN1 (1.00) | MEN1KMT2ATDP1APPTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4427033-B1 | METHOD FOR QUALITATIVE AND QUANTITATIVE DETERMINATION OF PROTEIN AGGREGATES | PAIA BIOTECH GMBH (DE) | 2026-05-20 | — | — | EP | claimed |
| WO-2025224727-A1 | p53 amyloid-binding composition, method, and kit thereof | INDIAN INSTITUTE OF TECHNOLOGY BOMBAY (IN) | 2025-10-30 | — | — | WO | claimed |
| EP-4427033-A1 | METHOD FOR THE QUALITATIVE AND QUANTITATIVE DETERMINATION OF PROTEIN AGGREGATES | PAIA Biotech GmbH (DE) | 2024-09-11 | — | — | EP | claimed |
| US-20240066153-A1 | CEST-MRI Methods for Detection of Diseases | ALBATANY MOHAMMED ABDELRAHEEM (CA) | 2024-02-29 | — | — | US | claimed |
| EP-4292654-A2 | DETECTION OF MISFOLDED PROTEINS | Board of Regents of the University of Texas System (US) | 2023-12-20 | — | — | EP | claimed |
| US-20230147467-A1 | Novel Contrast Agents and Imaging Methods for Early Detection of Diseases | ALGBURI ISHTAR FAISAL (CA) | 2023-05-11 | — | — | US | claimed |
| WO-2023079052-A1 | METHOD FOR THE QUALITATIVE AND QUANTITATIVE DETERMINATION OF PROTEIN AGGREGATES | PAIA BIOTECH GMBH (DE) | 2023-05-11 | — | — | WO | claimed |
| US-20220313171-A1 | Imaging and Treatment Methods for Early Detection of Diseases | ALGBURI ISHTAR FAISAL (CA) | 2022-10-06 | — | — | US | claimed |
| US-12636385-B2 | Selective ligands for tau aggregates | SENTONIX, INC. (US) | 2026-05-26 | — | — | US | disclosed |
| EP-4427033-B1 | METHOD FOR QUALITATIVE AND QUANTITATIVE DETERMINATION OF PROTEIN AGGREGATES | PAIA BIOTECH GMBH (DE) | 2026-05-20 | — | — | EP | disclosed |
| US-20260133206-A1 | MISFOLDED PROTEIN DETECTION IN THE EYE | LACRISTAT LLC (US) | 2026-05-14 | — | — | US | disclosed |
| EP-4115976-B1 | REACTION VESSEL | ALOIS DATA GMBH (DE) | 2026-04-29 | — | — | EP | disclosed |
| EP-4724816-A2 | METHODS FOR DETECTING THE PRESENCE OF AT LEAST ONE MISFOLDED FORM OF SOD1 IN A BIOLOGICAL SAMPLE | Mclaughlin Research Institute for Biomedical Sciences (US) | 2026-04-15 | — | — | EP | disclosed |
| US-12540949-B2 | Detection of misfolded alpha synuclein protein | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2026-02-03 | — | — | US | disclosed |
| EP-1110945-A2 | Azocompounds for the antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition | UNIVERSITY OF PITTSBURGH (US) | 2001-06-27 | — | — | EP | disclosed |
| US-6168776-B1 | Alkyl, alkenyl and alkynyl Chrysamine G derivatives for the antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition | UNIVERSITY OF PITTSBURGH | 2001-01-02 | — | — | US | disclosed |
| US-6133259-A | DIAGNOSIS OF ALZHEIMER'S DISEASE | UNIVERSITY OF PITTSBURGH (US) | 2000-10-17 | — | — | US | disclosed |
| US-6114175-A | AMYLOID-BINDING COMPOUNDS WHICH ARE NON-AZO DERIVATIVES OF CHRYSAMINE G TO DETERMINE DEGREE OF BRAIN DEPOSITS QUANTITATIVELY CHARACTERIZED BY AMYLOIDOSIS; DOWN'S SYNDROME; PREVENT CELL DEGENERATION; RADIOACTIVE IMAGING | UNIVERSITY OF PITTSBURGH (US) | 2000-09-05 | — | — | US | disclosed |
| US-4058607-A | DIHALOVINYL DIALKYL PHOSPHATE, 1,3-BENZODIOXOLES | AIRWICK INDUSTRIES, INC. (US) | 1977-11-15 | — | — | US | disclosed |
| US-3966900-A | INSECTICIDES | AIRWICK INDUSTRIES, INC. (US) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12540949-B2 | Detection of misfolded alpha synuclein protein | SNCA, PARK7, NEFM | MEN1 4600/4885KMT2A 4703/4885TDP1 452/4885 |
| US-12636385-B2 | Selective ligands for tau aggregates | MAPT, PSEN2, PSEN1 | MEN1 1162/4885KMT2A 4385/4885TDP1 757/4885 |
| US-20260133206-A1 | MISFOLDED PROTEIN DETECTION IN THE EYE | SNCA, SAAL1, PRNP | MEN1 2655/4885KMT2A 4655/4885TDP1 996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.