Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CDK4 | P11802 | 1/20 | 0.49 |
| ▸ | CCND1 | P24385 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1581511 | 0.88 | KMT2A (0.53) | MTNR1AMTNR1BLMNAKMT2ACDK4 | |
| SCHEMBL5449468 | 0.81 | LMNA (0.50) | MTNR1AMTNR1BLMNACDK4CCND1 | |
| SCHEMBL1581454 | 0.80 | MTNR1A (0.50) | MTNR1AACHE | |
| SCHEMBL15526048 | 0.79 | KRAS (0.47) | LMNAACHE | |
| SCHEMBL4290177 | 0.78 | LMNA (0.45) | MTNR1AMTNR1BLMNAKMT2ACDK4 | |
| SCHEMBL26192630 | 0.77 | CDK4 (0.50) | CDK4CCND1ACHE | |
| SCHEMBL1581855 | 0.77 | LMNA (0.67) | LMNAACHE | |
| SCHEMBL9635379 | 0.76 | CDK4 (0.56) | MTNR1AMTNR1BLMNACDK4CCND1 | |
| Hydrochloric Acid SCHEMBL4292429 | 0.76 | LMNA (0.43) | MTNR1AMTNR1BLMNAKMT2ACDK4 | |
| Hydrochloric Acid SCHEMBL4293143 | 0.76 | LMNA (0.43) | MTNR1AMTNR1BLMNAKMT2ACDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720872-B1 | ARYL AND HETEROARYL-PIPERIDINECARBOXYLATE DERIVATIVES, THE PREPARATION AND THE USE THEREOF IN THE FORM OF FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2011-04-20 | — | — | EP | disclosed |
| EP-1720872-A1 | ARYL AND HETEROARYL-PIPERIDINECARBOXYLATE DERIVATIVES, THE PREPARATION AND THE USE THEREOF IN THE FORM OF FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005090347-A1 | ARYL AND HETEROARYL-PIPERIDINECARBOXYLATE DERIVATIVES, THE PREPARATION AND THE USE THEREOF IN THE FORM OF FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |